Evidence map›Paper›PMID 38304780›Full record

ArticleHeliyon2024

YOLO and residual network for colorectal cancer cell detection and counting.

Inayatul Haq, Tehseen Mazhar, Rizwana Naz Asif, Yazeed Yasin Ghadi, Najib Ullah, Muhammad Amir Khan, Amal Al-Rasheed

Abstract read
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Inayatul HaqSchool of Electrical and Information Engineering, Zhengzhou University, Zhengzhou, 450001, China.
Tehseen MazharDepartment of Computer Science, Virtual University of Pakistan, Lahore, 55150, Pakistan.
Rizwana Naz AsifSchool of Computer Science, National College of Business Administration and Economics, Lahore, 54000, Pakistan.
Yazeed Yasin GhadiDepartment of Computer Science and Software Engineering, Al Ain University, Abu Dhabi, 12555, United Arab Emirates.
Najib UllahFaculty of Pharmacy and Health Sciences, Department of Pharmacy, University of Balochistan, Quetta, 08770, Pakistan.
Muhammad Amir KhanSchool of Computing Sciences, College of Computing, Informatics and Mathematics, Universiti Teknologi MARA, 40450, Shah Alam, Selangor, Malaysia.
Amal Al-RasheedDepartment of Information Systems, College of Computer and Information Sciences, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The HT-29 cell line, derived from human colon cancer, is valuable for biological and cancer research applications. Early detection is crucial for improving the chances of survival, and researchers are introducing new techniques for accurate cancer diagnosis. This study introduces an efficient deep learning-based method for detecting and counting colorectal cancer cells (HT-29). The colorectal cancer cell line was procured from a company. Further, the cancer cells were cultured, and a transwell experiment was conducted in the lab to collect the dataset of colorectal cancer cell images via fluorescence microscopy. Of the 566 images, 80 % were allocated to the training set, and the remaining 20 % were assigned to the testing set. The HT-29 cell detection and counting in medical images is performed by integrating YOLOv2, ResNet-50, and ResNet-18 architectures. The accuracy achieved by ResNet-18 is 98.70 % and ResNet-50 is 96.66 %. The study achieves its primary objective by focusing on detecting and quantifying congested and overlapping colorectal cancer cells within the images. This innovative work constitutes a significant development in overlapping cancer cell detection and counting, paving the way for novel advancements and opening new avenues for research and clinical applications. Researchers can extend the study by exploring variations in ResNet and YOLO architectures to optimize object detection performance. Further investigation into real-time deployment strategies will enhance the practical applicability of these models.

Indexed as

Biomedical image processingColon cancerComputer-aided diagnosisDeep learningHT-29 cellsMachine learningMedical image analysis

Identifiers

PMID38304780
PMCPMC10831604

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.