Evidence map›Paper›PMID 38304758›Full record

ArticleIJID regions2024

Human T-lymphotropic virus-1 infection among Latin American pregnant women living in Spain.

Begoña Encinas, Rafael Benito, Silvia Rojo, Gabriel Reina, Natalia Montiel, Antonio Aguilera, José María Eiros, Juan García-Costa, Diego Ortega, Irene Arco and 4 more

Open access · goldAbstract read
In one paragraph

Article in IJID regions, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 12 institutions in 1 country.

Begoña EncinasGynecology & Obstetrics Department, Puerta de Hierro University Hospital, Madrid, Spain.
Rafael BenitoMicrobiology Department, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
Silvia RojoMicrobiology Department, Hospital Clínico Universitario, Valladolid, Spain.
Gabriel ReinaMicrobiology Department, Clínica Universidad de Navarra, Pamplona, Spain.
Natalia MontielMicrobiology Department, Hospital Universitario Puerta del Mar, Cádiz, Spain.
Antonio AguileraMicrobiology Department, University of Santiago, Santiago de Compostela, Spain.
José María EirosMicrobiology Department, Rio Hortega University Hospital, Valladolid, Spain.
Juan García-CostaMicrobiology Department, Complejo Hospitalario de Ourense, Ourense, Spain.
Diego OrtegaMicrobiology Department, Hospital Miguel Servet, Zaragoza, Spain.
Irene ArcoMicrobiology Department, General University Hospital of Alicante, Pintor Baeza, Alicante, Spain.
Araceli Hernánez-BatancorMicrobioligy Department, Hospital insular Unidad De Traslados, Avenida Maritima del Sur, Las Palmas de Gran Canaria, Spain.
Vicente SorianoInternational University of La Rioja (UNIR) Health Sciences School & Medical Center, Madrid, Spain.
Carmen de MendozaPuerta de Hierro University Hospital & Research Foundation-IDIPHISA, Madrid, Spain.
Spanish HTLV Network
Hospital Universitario Puerta de Hierro Majadahonda · ESClinica Universidad de Navarra · ESComplejo Hospitalario de Ourense · ESHospital Clínico Universitario de Valladolid · ESHospital Clínico Universitario Lozano Blesa · ESHospital General Universitario de Alicante Doctor Balmis · ESHospital Universitario Insular de Gran Canaria · ESHospital Universitario Miguel Servet · ESHospital Universitario Río Hortega · ESUniversidad de Cádiz · ESUniversidade de Santiago de Compostela · ESUniversidad Internacional De La Rioja · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Human T-lymphotropic virus (HTLV) antenatal screening is not mandatory in Spain. Surveys conducted decades ago reported HTLV-1 seroprevalence rates of 0.2% among foreign pregnant women in Spain. The migrant flow to Spain from HTLV-1 endemic regions in Latin America and sub-Saharan Africa has increased during the last decade. Currently, 25% of pregnant women in Spain are foreigners. Methods: From January 2021 to October 2023 a cross-sectional study was carried out in all consecutive pregnant women attended at eleven Spanish clinics. A commercial enzyme immunoassay (EIA) was used for screening of serum HTLV-1/2 antibodies. Reactive samples were confirmed by immunoblot. Results: A total of 9813 pregnant women with a median age of 34 years-old were examined. Native Spaniards were 6977 (76.5%). Of 2147 foreigners (23.5%), 903566 (9.9%) were Latin Americans, 416 (4.5%) North Africans, 293 (3.2%) from Romania, and 196 (2.1%) from sub-Saharan Africa. A total of 47 samples were EIA reactive but only five were confirmed as HTLV-1 positive using immunoblot. Infected women came from Paraguay, Colombia, the Dominican Republic, Venezuela and Peru. All but one were primigravida, with ages ranging from 20 to 33 years-old. One was HIV-1 positive, and another was infected with Conclusion: The overall seroprevalence for HTLV-1 among pregnant women in Spain is 0.05% but rises ten-fold (0.55%) among Latin Americans. This rate is higher than in surveys conducted decades ago. Our results support that anti-HTLV testing should be part of antenatal screening in Spain in pregnant women coming from Latin America, as it is already done with Chagas disease.

Indexed as

BreastfeedingHTLV-1MigrationPregnant womenVertical transmission

Identifiers

PMID38304758
PMCPMC10831283
OpenAlexW4388914784

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.