ArticleCritical care explorations2023
Continuous Renal Replacement Therapy and Mortality in Critically Ill Obese Adults.
Article in Critical care explorations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 4 citations in OpenAlex.
- Prognostic Factors of 30-Day In-Hospital Mortality in Critically Ill Patients Receiving Continuous Renal Replacement Therapy.The journal of nursing research : JNR · 2026Observational
- Association between obesity and kidney outcomes in critically ill patients with acute kidney injury receiving continuous renal replacement therapy: a secondary analysis of the multicenter CRRTnet study.Critical care (London, England) · 2026Observational
- Obesity and mortality in KDIGO stage 3 acute kidney injury: a machine learning-driven retrospective cohort study.BMC nephrology · 2025Article
- Intensive care unit continuous kidney replacement therapy: time to change dosage recommendations?International urology and nephrology · 2025Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
importanceThe outcomes of critically ill adults with obesity on continuous renal replacement therapy (CRRT) are poorly characterized. The impact of CRRT dose on these outcomes is uncertain.
objectivesThis study aimed to determine if obesity conferred a survival advantage for critically ill adults with acute kidney injury (AKI) on CRRT. Secondarily, we evaluated whether the dose of CRRT predicted mortality in this population. DESIGN SETTING AND
participantsA retrospective, observational cohort study performed at an academic medical center in Minnesota. The study population included critically ill adults with AKI managed with CRRT. MAIN OUTCOMES AND MEASURES: The primary outcome of 30-day mortality was compared between obese (body mass index [BMI] ≥ 30 kg/m
resultsAmong 1033 included patients, the median (interquartile range) BMI was 26 kg/m CONCLUSIONS AND RELEVANCE: In critically ill adults with AKI requiring CRRT, short-term mortality appeared lower in obese patients compared with nonobese patients. Among weight calculations, IBW appears to be preferred to promote safe CRRT dosing in obese patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.