Evidence map›Paper›PMID 38304655›Full record

ArticleCureus2024

Intensifying the Hormonal and Radiation Treatment in Prostate Cancer Presenting With Bulky Pelvic Lymph Nodes: An Opportunity for a New Paradigm.

Agha H Khan, Nadeem Pervez, Muhammad S Usmani, Houda S Almusalhi, Munjid Al Harthy, Layth Mula-Hussain

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Agha H KhanRadiation Oncology, McGill University, Montreal, CAN.
Nadeem PervezRadiation Oncology, Sultan Qaboos Comprehensive Cancer Care and Research Centre, Muscat, OMN.
Muhammad S UsmaniNuclear Medicine, Sultan Qaboos Comprehensive Cancer Care and Research Centre, Muscat, OMN.
Houda S AlmusalhiRadiation Oncology, Sultan Qaboos University, Muscat, OMN.
Munjid Al HarthyMedical Oncology, Sultan Qaboos Comprehensive Cancer Care and Research Centre, Muscat, OMN.
Layth Mula-HussainRadiation Oncology, Sultan Qaboos Comprehensive Cancer Care and Research Centre, Muscat, OMN.
Dalhousie University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Locally advanced prostate cancer may rarely present with bulky pelvic lymph nodes without distant metastasis. Patients may be treated with curative intent. Dual hormonal therapy including luteinizing hormone-releasing hormone agonist in combination with abiraterone or enzalutamide can be utilized neoadjuvantly to shrink bulky disease. This can be followed by radical doses of radiotherapy. This intensified treatment is tolerable. Prostate-specific membrane antigen scan can be utilized to assess staging and treatment response. Here, we present a case of a non-metastatic locally advanced prostate cancer with bulky pelvic lymph nodes. The patient was treated neoadjuvantly with dual hormonal therapy followed by radical doses of radiotherapy. The patient tolerated the treatment well and had a promising early response.

Indexed as

bulky lymph nodesduo hormonal therapyhypofractionated rtintensity-modulated radiation therapy (imrt)locally advancedprostate cancerpsma scanradical treatmentradiotherapy

Identifiers

PMID38304655
PMCPMC10832942
OpenAlexW4390499343

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.