Evidence map›Paper›PMID 38304578›Full record

ReviewFrontiers in molecular biosciences2024

Ssu72: a versatile protein with functions in transcription and beyond.

Emma Fidler, Katherine Dwyer, Athar Ansari

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Emma FidlerDepartment of Biological Sciences, Wayne State University, Detroit, MI, United States.
Katherine DwyerDepartment of Biological Sciences, Wayne State University, Detroit, MI, United States.
Athar AnsariDepartment of Biological Sciences, Wayne State University, Detroit, MI, United States.
Wayne State University · US

Funding

A new paradigm of general transcription factor TFIIB functionality in termination and promoter directionalityR01GM146803 · NIGMS · WAYNE STATE UNIVERSITY · PI Athar Imtiaz Ansari · 2022 to 2026
$1.6M
NIGMS NIH HHS R01 GM146803
6 · The paper itself

Abstract

Eukaryotic transcription is a complex process involving a vast network of protein and RNA factors that influence gene expression. The main player in transcription is the RNA polymerase that synthesizes the RNA from the DNA template. RNA polymerase II (RNAPII) transcribes all protein coding genes and some noncoding RNAs in eukaryotic cells. The polymerase is aided by interacting partners that shuttle it along the gene for initiation, elongation and termination of transcription. One of the many factors that assist RNAPII in transcription of genes is Ssu72. It is a carboxy-terminal-domain (CTD)-phosphatase that plays pleiotropic roles in the transcription cycle. It is essential for cell viability in

Indexed as

CTDgene loopinggene regulationliver and autoimmune diseasesterminationtranscription

Identifiers

PMID38304578
PMCPMC10830811
OpenAlexW4390981660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.