ArticleFrontiers in radiology2023
High resolution and contrast 7 tesla MR brain imaging of the neonate.
Article in Frontiers in radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Imaging of Embryonic and Fetal Brain Development Using MRI Microscopy: Achieving High Spatial Resolution.Medical sciences (Basel, Switzerland) · 2026Review
- Potential Benefits of Ultra-High Field MRI for Embryonic and Fetal Brain Investigation: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2026Review
- A size-adaptive RF coil for MRI of the pediatric human brain at 7 T.Magnetic resonance in medicine · 2025Article
- 7 Tesla fMRI characterisation of the cortical-depth-dependent BOLD response in early human development.bioRxiv : the preprint server for biology · 2025Article
- fMRIPrep Lifespan: Extending A Robust Pipeline for Functional MRI Preprocessing to Developmental Neuroimaging.bioRxiv : the preprint server for biology · 2025Article
- TMagnetic resonance in medicine · 2025Article
- A closer look: pediatric neuroimaging at 7T.Pediatric radiology · 2025Review
- Review of 7T MRI imaging of pituitary microadenomas: are we there yet?Neuroradiology · 2025Review
- Functional organization of the neonatal thalamus across development depicted by functional MRI.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Advances in fetal and neonatal neuroimaging and everyday exposures.Pediatric research · 2024Review
Corrections and comments
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Authors and funding
32 authors at 5 institutions in 2 countries.
Funding
Abstract
Introduction: Ultra-high field MR imaging offers marked gains in signal-to-noise ratio, spatial resolution, and contrast which translate to improved pathological and anatomical sensitivity. These benefits are particularly relevant for the neonatal brain which is rapidly developing and sensitive to injury. However, experience of imaging neonates at 7T has been limited due to regulatory, safety, and practical considerations. We aimed to establish a program for safely acquiring high resolution and contrast brain images from neonates on a 7T system. Methods: Images were acquired from 35 neonates on 44 occasions (median age 39 + 6 postmenstrual weeks, range 33 + 4 to 52 + 6; median body weight 2.93 kg, range 1.57 to 5.3 kg) over a median time of 49 mins 30 s. Peripheral body temperature and physiological measures were recorded throughout scanning. Acquired sequences included T2 weighted (TSE), Actual Flip angle Imaging (AFI), functional MRI (BOLD EPI), susceptibility weighted imaging (SWI), and MR spectroscopy (STEAM). Results: There was no significant difference between temperature before and after scanning ( Discussion: We demonstrate safety and feasibility of imaging vulnerable neonates at ultra-high field and highlight the untapped potential for providing important new insights into brain development and pathological processes during this critical phase of early life.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.