Evidence map›Paper›PMID 38304252›Full record

ArticleFrontiers in immunology2023

Inhibition of anti-tumor immunity by melanoma cell-derived Activin-A depends on STING.

Katarina Pinjusic, Giovanna Ambrosini, Joao Lourenco, Nadine Fournier, Christian Iseli, Nicolas Guex, Olga Egorova, Sina Nassiri, Daniel B Constam

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. LncRNA AC098613.1 promotes acute myeloid leukemia cell differentiation through CDC5L/ADAP1/NRD1 axis.Apoptosis : an international journal on programmed cell death · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Katarina PinjusicEcole Polytechnique Fédérale de Lausanne (EPFL), SV ISREC, Lausanne, Switzerland.
Giovanna AmbrosiniBioinformatics Competence Center, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Joao LourencoTranslational Data Science Facility, Swiss Institute of Bioinformatics, AGORA Cancer Research Center, Lausanne, Switzerland.
Nadine FournierTranslational Data Science Facility, Swiss Institute of Bioinformatics, AGORA Cancer Research Center, Lausanne, Switzerland.
Christian IseliBioinformatics Competence Center, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Nicolas GuexBioinformatics Competence Center, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Olga EgorovaEcole Polytechnique Fédérale de Lausanne (EPFL), SV ISREC, Lausanne, Switzerland.
Sina NassiriTranslational Data Science Facility, Swiss Institute of Bioinformatics, AGORA Cancer Research Center, Lausanne, Switzerland.
Daniel B ConstamEcole Polytechnique Fédérale de Lausanne (EPFL), SV ISREC, Lausanne, Switzerland.
École Polytechnique Fédérale de Lausanne · CHSIB Swiss Institute of Bioinformatics · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transforming growth factor-β (TGF-β) family member activin A (hereafter Activin-A) is overexpressed in many cancer types, often correlating with cancer-associated cachexia and poor prognosis. Activin-A secretion by melanoma cells indirectly impedes CD8

Indexed as

ActivinsMelanomaTransforming Growth Factor betaTumor EscapeAnimalsMiceSignal TransductionTumor Microenvironmentactivin AActivinsTransforming Growth Factor betaactivincancerintercellular communicationinterferonknockdownprofilingscRNA-seqSTING

Identifiers

PMID38304252
PMCPMC10830842
OpenAlexW4390981816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.