Evidence map›Paper›PMID 38304196›Full record

ArticleFrontiers in cellular and infection microbiology2024

Lujuan Gao, Xuqiong Xia, Xiao Gong, Heng Zhang, Yi Sun

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Oxidoreductase geneMicrobiology spectrum · 2026
    Article
  2. Article
  3. Article
  4. Baicalein combined with azoles against fungiFrontiers in microbiology · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Lujuan Gao *Department of Dermatology, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian, China.
Xuqiong Xia *Department of Dermatology, Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiao GongDepartment of Dermatology, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, Hubei, China.
Heng ZhangDepartment of Dermatology, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, Hubei, China.
Yi SunDepartment of Dermatology, Jingzhou Hospital Affiliated to Yangtze University, Jingzhou, Hubei, China.
Yangtze University · CNShanghai Ninth People's Hospital · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Azole resistance has been increasingly reported and become an issue for clinical managements of invasive mycoses. New strategy with combination therapy arises as a valuable and promising alternative option. The aim of the present study is to investigate the Methods: Results: PPIs individually did not exert any significant antifungal activity. The combination of OME with ITC, POS, or VRC showed synergism against 77.6%, 86.6%, and 4% strains of tested pathogenic fungi, respectively, while synergism of OME/FLC was observed in 50% strains of Discussion: The results suggested that PPIs combined with azoles has the potential to enhance the susceptibilities of azoles against multiple pathogenic fungi and could be a promising strategy to overcome azole resistance issues. However, further investigations are warranted to study the combinational efficacy in more isolates and more species, to investigate the underlying mechanism of interaction and to evaluate the potential for concomitant use of these agents in human.

Indexed as

AzolesProton Pump InhibitorsAntifungal AgentsAspergillusCandidaCandida parapsilosisDrug Resistance, FungalFluconazoleFungiHumansMicrobial Sensitivity TestsTriazolesVoriconazoleAntifungal AgentsAzolesFluconazoleProton Pump InhibitorsTriazolesVoriconazoleAspergillusazoleCandidadematiaceous fungifungiomeprazolepantoprazoleproton pump inhibitors

Identifiers

PMID38304196
PMCPMC10831725
OpenAlexW4390953681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.