Evidence map›Paper›PMID 38303957›Full record

ArticleChemical science2024

A metal-free strategy to construct fluoroalkyl-olefin linkages using fluoroalkanes.

Kaushik Chakrabarti, Michael M Wade Wolfe, Shuo Guo, Joseph W Tucker, Jisun Lee, Nathaniel K Szymczak

Abstract read
In one paragraph

Article in Chemical science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kaushik ChakrabartiDepartment of Chemistry, University of Michigan, 930 N. University Ann Arbor Michigan 48109 USA nszym@umich.edu.
Michael M Wade WolfeDepartment of Chemistry, University of Michigan, 930 N. University Ann Arbor Michigan 48109 USA nszym@umich.edu.
Shuo GuoCollege of Chemistry and Chemical Engineering, Inner Mongolia University Hohhot 010021 P.R. China.ORCID https://orcid.org/0000-0002-3042-9209
Joseph W TuckerMedicine Design, Pfizer Inc. Eastern Point Rd Groton CT 06340 USA.
Jisun LeeMedicine Design, Pfizer Inc. Eastern Point Rd Groton CT 06340 USA.ORCID https://orcid.org/0000-0003-1750-0063
Nathaniel K SzymczakDepartment of Chemistry, University of Michigan, 930 N. University Ann Arbor Michigan 48109 USA nszym@umich.edu.ORCID https://orcid.org/0000-0002-1296-1445

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present a metal-free strategy to access fluoroalkyl-olefin linkages from fluoroalkane precursors and vinyl-pinacol boronic ester (BPin) reagents. This reaction sequence is templated by the boron reagent, which induces C-C bond formation upon oxidation. We developed this strategy into a one-pot synthetic protocol using RCF

Identifiers

PMID38303957
PMCPMC10829021

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.