ArticleJournal of dental sciences2024
In vitro cytotoxicity and antibacterial activity of hypochlorous acid antimicrobial agent.
Article in Journal of dental sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Effects of hypochlorous acid, povidone-iodine, and Carrel-Dakin solution irrigation on open fracture healing: a rat femur model.Journal of orthopaedic surgery and research · 2026Article
- Influence of Different Cavity Disinfection Protocols on Adhesion at the Resin Composite-Dentin Interface.Polymers · 2026Article
- Cellular senescence in the dental pulp and its implications for endodontics: a scoping review.Clinical oral investigations · 2026Article
- Application of slightly acidic electrolyzed water (SAEW) for surface disinfection in waste sorting and sewage treatment plants: a pilot study.International journal of occupational medicine and environmental health · 2026Article
- Antibacterial tannic acid/polydopamine hybrid coatings for titanium implants.Journal of dental sciences · 2026Article
- Hypochlorous Acid: Clinical Insights and Experience in Dermatology, Surgery, Dentistry, Ophthalmology, Rhinology, and Other Specialties.Biomedicines · 2025Review
- Hypochlorous acid as a potential cavity conditioner for caries-affected dentin.Scientific reports · 2025Article
- Phloxine B-loaded polymersomes enable eradication ofRSC advances · 2025Article
- Synergistic antibacterial effect of hydroxyl radicals generated by the combination of hypochlorous acid and UV irradiation.PloS one · 2025Article
- Antimicrobial action, cytotoxicity and erosive potential of hypochlorous acid obtained from an electrolytic device compared with sodium hypochlorite.Clinical oral investigations · 2024Article
- The HOCl dry fog-is it safe for human cells?PloS one · 2024Article
- Emerging treatments in fungal keratitis.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological SocietyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background/purpose: Bacteria-associated oral diseases such as dental caries and periodontitis are widespread epidemics that cause oral pain and loss of function. The purpose of this study was to evaluate the in vitro cytotoxicity and antibacterial activity of different concentrations of hypochlorous acid (HOCl). Materials and methods: Five different concentrations (100, 200, 300, 400, and 500 ppm) of HOCl were evaluated for their antimicrobial efficacy against Gram-negative ( Results: The bacteriostatic ratio of NaOCl was comparable to that of CHX and significantly ( Conclusion: Within the limit of this study, 400 ppm HOCl disinfectant may be a potential antimicrobial candidate for mouthwash, endodontic irrigants, and periodontitis treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.