Evidence map›Paper›PMID 38303833›Full record

ArticleJournal of dental sciences2024

Association of higher transient receptor potential melastatin 8 expression with higher tumor histologic grades, lymph node metastasis, risk factors, and worse survival in patients with head and neck squamous cell carcinoma.

Nan-Chin Lin, Thanh-Hien Vu Nguyen, Yin-Hwa Shih, Yi-Hung Chen, Yen-Wen Shen, Kuo-Chou Chiu, Shih-Min Hsia, Tzong-Ming Shieh

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of dental sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Nan-Chin LinSchool of Dentistry, China Medical University, Taichung, Taiwan.
Thanh-Hien Vu NguyenSchool of Dentistry, China Medical University, Taichung, Taiwan.
Yin-Hwa ShihDepartment of Healthcare Administration, Asia University, Taichung, Taiwan.
Yi-Hung ChenGraduate Institute of Acupuncture Science, China Medical University, Taichung, Taiwan.
Yen-Wen ShenSchool of Dentistry, China Medical University, Taichung, Taiwan.
Kuo-Chou ChiuDivision of General Dentistry, Taichung Armed Forces General Hospital, Taichung, Taiwan.
Shih-Min HsiaSchool of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan.
Tzong-Ming ShiehSchool of Dentistry, China Medical University, Taichung, Taiwan.
China Medical University · TWAsia University · TWTaichung Armed Forces General Hospital · TWTaipei Medical University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: Transient receptor potential melastatin 8 (TRPM8), a thermosensitive ion channel known for its role in cold sensation and menthol response, has emerged as a potential regulator in various cancers. This study aimed to investigate expression trends of TRPM8 in head and neck squamous cell carcinoma (HNSCC) cases and oral squamous cell carcinoma (OSCC) cell lines and its association with clinicopathological features. Materials and methods: The noncancerous matched tissues and HNSCC paired tissue samples from 84 HNSCC patients were utilized to evaluate the association of Results: Kaplan-Meier survival analysis of TCGA data revealed high Conclusion: These findings reveal the involvement of

Indexed as

ArecolineHead and neck squamous cell carcinomaLymph node metastasisOral squamous cell carcinomaTransient receptor potential melastatin 8

Identifiers

PMID38303833
PMCPMC10829716
OpenAlexW4386969450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.