Evidence map›Paper›PMID 38303677›Full record

ArticleThe International journal of eating disorders2024

Naturalistic symptom trajectories of atypical anorexia nervosa, anorexia nervosa, and bulimia nervosa in a prospective cohort study of United States college students.

Kelsey E Hagan, Adanya Johnson, Kira Venables, Amanda Makara, Spit for Science Working Group, Ann F Haynos

Open access · bronzeAbstract read
In one paragraph

Article in The International journal of eating disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
3.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Severity levels of anorexia nervosa and atypical anorexia nervosa in a Korean cohort.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kelsey E HaganDepartment of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0001-5723-3591
Adanya JohnsonDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0001-5314-4532
Kira VenablesDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0009-0001-3713-928X
Amanda MakaraDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-8101-2278
Spit for Science Working GroupInstitute for Research on Behavioral and Emotional Health, Virginia Commonwealth University, Richmond, Virginia, USA.
Ann F HaynosDepartment of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-2548-1731
Virginia Commonwealth University · USUniversity of Minnesota · US

Funding

Project 5 - Genetic architecture of alcohol use disorder using cross-trait genetic correlations and public next-generation sequencing studiesP50AA022537 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI JILL C BETTINGER · 2014 to 2026
$19.6M
Wright Regional Center for Clinical and Translational ScienceUM1TR004360 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI FREDERICK Gerard MOELLER · 2023 to 2026
$16.3M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR031990 · NCRR · VIRGINIA COMMONWEALTH UNIVERSITY · PI CLORE, JOHN N. · 2010 to 2011
$7.7M
An Alcohol Affected Sib Pair Study of Alcohol DependenceR37AA011408 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI KENDLER, KENNETH SEEDMAN · 2007 to 2016
$6.5M
Building Interdisciplinary Research Careers in Women's HealthK12AR084233 · NIAMS · VIRGINIA COMMONWEALTH UNIVERSITY · PI Barbara D. Boyan, SUSAN G. KORNSTEIN · 2023 to 2026
$2.2M
Project 3: Cross Species Characterization of Gene Networks in Acute ResponsesP20AA017828 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI BETTINGER, JILL C · 2009 to 2012
$2.2M
Twin, molecular, and developmental approaches to understanding alcohol misuseK02AA018755 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DICK, DANIELLE M · 2010 to 2019
$1.3M
Genetics, Romantic Relationships, and Alcohol Misuse in Emerging AdulthoodK01AA024152 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI SALVATORE, JESSICA E · 2016 to 2020
$741k
NCATS NIH HHS UM1 TR004360NCATS NIH HHS UM1TR004360NCRR NIH HHS UL1 RR031990NCRR NIH HHS UL1RR031990NIAAA NIH HHS K01 AA024152NIAAA NIH HHS K01AA024152NIAAA NIH HHS K02 AA018755NIAAA NIH HHS K02AA018755NIAAA NIH HHS P20 AA017828NIAAA NIH HHS P20AA017828NIAAA NIH HHS P50 AA022537NIAAA NIH HHS P50AA022537NIAAA NIH HHS R37 AA011408NIAAA NIH HHS R37AA011408NIAMS NIH HHS K12 AR084233
6 · The paper itself

Abstract

objectiveResearch on the natural course of symptoms of atypical anorexia nervosa (AN) relative to AN and bulimia nervosa (BN) is limited yet needed to inform nosology and improve understanding of atypical AN. This study aimed to 1) characterize trajectories of eating disorder and internalizing (anxiety, depression) symptoms in college students with and without a history of atypical AN, AN, and BN; and 2) compare sex and race/ethnicity distributions across groups.

methodUnited States college students who participated in Spit for Science™, a prospective cohort study, were classified as having a history of atypical AN (n = 125), AN (n = 160), BN (n = 617), or as non-eating-disorder controls (NCs, n = 5876). Generalized and linear mixed-effects models assessed group differences in eating and internalizing symptom trajectories, and logistic regression compared groups on sex and race/ethnicity distributions.

resultsAtypical AN participants demonstrated elevated eating disorder and internalizing symptoms compared to NCs during college, but less severe symptoms than AN and BN participants. Although all eating disorder groups showed signs of improvement in fasting and driven exercise, purging and depression remained elevated. Atypical AN participants showed increasing anxiety and stable binge-eating trajectories compared to AN and/or BN participants. The atypical AN group comprised significantly more people of color than the AN group. DISCUSSION: Findings underscore that atypical AN is a severe psychiatric disorder. As atypical AN may present as less severe than AN and BN and disproportionately affects people of color, clinicians should be mindful of biases that could delay diagnosis and care. PUBLIC SIGNIFICANCE: College students with histories of atypical AN, AN, and BN demonstrated improvements in fasting and driven exercise and stable purging and depression levels. Atypical AN students showed worsening anxiety and stable binge-eating trajectories compared to favorable changes among AN and BN students. A higher percentage of atypical AN (vs. AN) students were people of color. Findings may improve the detection of atypical AN in college students.

Indexed as

Anorexia NervosaBinge-Eating DisorderBulimia NervosaAnxietyHumansProspective Studiesanorexia nervosaatypical anorexia nervosabulimia nervosacollege mental healthnatural coursesymptom trajectories

Identifiers

PMID38303677
PMCPMC11018494
OpenAlexW4391477224

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.