Evidence map›Paper›PMID 38302946›Full record

ArticleBMC public health2024

Acute and persistent symptoms of COVID-19 infection in school-aged children: a retrospective study from China.

Honglin Wang, Fangfang Lu, Xiuxian Ni, Rijing Luo, Linxiang Chen, Jing Yuan, Zhen Zhang, Qiuying Lv

Abstract read
In one paragraph

Article in BMC public health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Honglin Wang *Department of Communicable Diseases Control and Prevention, Shenzhen Center for Disease Control and Prevention, 8 Longyuan Rd, 518055, Shenzhen, China.
Fangfang Lu *Disease Control Division, Public Health Service Center, Bao'an District, 518103, Shenzhen, China.
Xiuxian NiDisease Control Division, Public Health Service Center, Bao'an District, 518103, Shenzhen, China.
Rijing LuoDepartment of Epidemiology, School of Public Health, (Guangdong Provincial Key Laboratory of Tropical Disease Research), Southern Medical University, 510515, Guangzhou, China.
Linxiang ChenDepartment of Immunization Planning, Luohu District Center for Disease Control and Prevention, 518020, Shenzhen, China.
Jing YuanShenzhen Key Laboratory of Pathogen and Immunity, State Key Discipline of Infectious Disease, Shenzhen Third People's Hospital, Second Hospital, National Clinical Research Center for Infectious Disease, Southern University of Science and Technology, 518112, Shenzhen, China.
Zhen ZhangDepartment of Communicable Diseases Control and Prevention, Shenzhen Center for Disease Control and Prevention, 8 Longyuan Rd, 518055, Shenzhen, China. zhangzhen@wjw.sz.gov.cn.
Qiuying LvDepartment of Communicable Diseases Control and Prevention, Shenzhen Center for Disease Control and Prevention, 8 Longyuan Rd, 518055, Shenzhen, China. sandylv1980@126.com.

Funding

Shenzhen Key Medical Discipline Construction Fund SZXK064Shenzhen San-Ming Project of Medicine in Shenzhen SZSM202011008The Key Project of Shenzhen Science and Technology Innovation Commission JCYJ202103241154-11030
6 · The paper itself

Abstract

backgroundThe long-term sequelae of Coronavirus disease 2019 (COVID-19) in children are unclear. We investigated COVID-19 symptoms in school-aged children to determine their impact on patients and their families.

methodsThis cross-sectional study, conducted on February 25-28, 2023, selected a representative kindergarten and 9-year school from Shenzhen, China. There were randomly two classes each for the 12 grades from kindergarten to junior high school. The school-aged children were aged 3-16 years. Literate parents completed an online questionnaire related to their children's COVID-19 symptoms since December 1, 2022. Descriptive statistics were computed as necessary. Univariate and multivariable linear regression analyses were performed, and variables with a p-value < 0.05 were considered to have a significant association with the subjective feeling scores for COVID-19 infection.

resultsWe included 936 school-aged children, with a COVID-19 infection rate of 68.5%. The prevalence of LC 28 (illness with symptoms lasting for 28 days) was 3.4%. During acute infection, the median number of the 641 children's symptoms was 3.0 (IQR: 1.0-5.0) and the median score of subjective feelings was 15.0 (IQR: 11.0-24.5). The top three symptoms were fever, cough/expectoration, and rhinobyon. Age of 13-16 years (adjusted beta: 3.60, 95% CI: 0.32-6.88) and comorbidities (adjusted beta: 3.47, 95% CI: 1.20-5.73) were independently associated with higher subjective feelings (p < 0.05). The top three characteristics associated with LC 28 were alopecia (33.3%, 5/15), cognitive dysfunction (29.2%, 7/24), and emotional problem (28.6%, 6/21).

conclusionsChildren with COVID-19 have a short duration of symptoms and milder symptoms, so they can self-medicate to minimize hospital crowding. Children with basic diseases require prompt attention. Although LC 28 is uncommon in children, mental and psychological problems after COVID-19 recovery should not be ignored.

Indexed as

COVID-19ChildChinaComorbidityCross-Sectional StudiesHumansRetrospective StudiesSARS-CoV-2COVID-19 infectionLong COVIDSARS-Cov-2School-aged childrenSymptoms

Identifiers

PMID38302946
PMCPMC10835839

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.