Evidence map›Paper›PMID 38302896›Full record

ArticleBMC microbiology2024

Identification of Campylobacter jejuni and Campylobacter coli genes contributing to oxidative stress response using TraDIS analysis.

Emily Stoakes, Xuanlin Chen, Lajos Kalmar, Dave Baker, Rhiannon Evans, Steven Rudder, Andrew J Grant

Abstract read
In one paragraph

Article in BMC microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Aerotolerancy ofPathogens (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emily StoakesDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, UK.
Xuanlin ChenDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, UK.
Lajos KalmarMRC Toxicology Unit, University of Cambridge, Tennis Court Road, Cambridge, UK.
Dave BakerQuadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Rhiannon EvansQuadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Steven RudderQuadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Andrew J GrantDepartment of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, UK. ajg60@cam.ac.uk.

Funding

Biotechnology and Biological Sciences Research Council BB/R012504/1Biotechnology and Biological Sciences Research Council BB/X011011/1Biotechnology and Biological Sciences Research Council BB/X018814/Biotechnology and Biological Sciences Research Council Institute Strategic Programme Microbes in the Food Chain [BB/R012504/1 and its constituent project BBS/E/F000PR10349 (Theme 2, Microbial Survival in the Food Chain]; and the Quadram Institute Bioscience funded Core Capability Grant [BB/CCG1860/1]; BBSRC Institute Strategic Programme Microbes and Food Safety BB/X011011/1 and its partner project BB/X018814/
6 · The paper itself

Abstract

backgroundCampylobacter jejuni and Campylobacter coli are the major causative agents of bacterial gastroenteritis worldwide and are known obligate microaerophiles. Despite being sensitive to oxygen and its reduction products, both species are readily isolated from animal food products kept under atmospheric conditions where they face high oxygen tension levels.

resultsIn this study, Transposon Directed Insertion-site Sequencing (TraDIS) was used to investigate the ability of one C. jejuni strain and two C. coli strains to overcome oxidative stress, using H

conclusionsThis is the first study to investigate gene fitness in both C. jejuni and C. coli under oxidative stress conditions and highlights both similar roles for certain genes for both species and highlights other genes that have a role under oxidative stress.

Indexed as

Campylobacter coliCampylobacter InfectionsCampylobacter jejuniAnimalsBacterial ProteinsHydrogen PeroxideOxidative StressOxygenBacterial ProteinsHydrogen PeroxideOxygenAerobic stressCampylobacter coliCampylobacter jejuniOxidative stressTraDIS

Identifiers

PMID38302896
PMCPMC10832277

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.