Evidence map›Paper›PMID 38302824›Full record

ReviewAlcohol, clinical & experimental research2024

Machine learning approaches to the identification of children affected by prenatal alcohol exposure: A narrative review.

Michael Suttie, Julie Kable, Amanda H Mahnke, Gretchen Bandoli

Abstract readReview
In one paragraph

Review in Alcohol, clinical & experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michael SuttieNuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, UK.
Julie KableDepartments of Psychiatry and Behavioral Science and Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-5008-0887
Amanda H MahnkeDepartment of Neuroscience and Experimental Therapeutics, Texas A&M University School of Medicine, Bryan, Texas, USA.
Gretchen BandoliDepartment of Pediatrics, University of California San Diego, La Jolla, California, USA.ORCID https://orcid.org/0000-0003-2167-8921

Funding

Image Analysis of Neurofacial Effects of Prenatal AlcoholExposureU01AA014809 · NIAAA · UNIVERSITY OF OXFORD · PI Michael Suttie · 2007 to 2026
$5.8M
Fetal Alcohol Spectrum Disorders in Adults: Health and NeurobehaviorU01AA026108 · NIAAA · EMORY UNIVERSITY · PI Tamara Sonia Bodnar, Claire D. Coles · 2017 to 2026
$3.9M
Applying Machine Learning in the Prediction and Identification of Children Affected by Prenatal Alcohol ExposureK01AA027811 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BANDOLI, GRETCHEN E. · 2019 to 2023
$865k
NIAAA NIH HHS 1K01 AA027811-01NIAAA NIH HHS K01 AA027811NIAAA NIH HHS U01 AA014809NIAAA NIH HHS U01 AA026108
6 · The paper itself

Abstract

Fetal alcohol spectrum disorders (FASDs) affect at least 0.8% of the population globally. The diagnosis of FASD is uniquely complex, with a heterogeneous physical and neurobehavioral presentation that requires multidisciplinary expertise for diagnosis. Many researchers have begun to incorporate machine learning approaches into FASD research to identify children who are affected by prenatal alcohol exposure, including those with FASD. This narrative review highlights these efforts. Following an introduction to machine learning, we summarize examples from the literature of neurobehavioral screening tools and physiologic markers of exposure. We discuss individual efforts, including models that classify FASD based on parent-reported neurocognitive or behavioral questionnaires, 3D facial imaging, brain imaging, DNA methylation patterns, microRNA profiles, cardiac orienting response, and dysmorphic facial features. We highlight model performance and discuss the limitations of these approaches. We conclude by considering the scalability of these approaches and how these machine learning models, largely developed from clinical samples or highly exposed birth cohorts, may perform in the general population.

Indexed as

fetal alcohol spectrum disordersmachine learningprenatal alcohol exposure

Identifiers

PMID38302824
PMCPMC11015982

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.