Evidence map›Paper›PMID 38302516›Full record

ArticleScientific reports2024

Central auditory test performance predicts future neurocognitive function in children living with and without HIV.

Jeff Joseph, Christopher Niemczak, Jonathan Lichtenstein, Anastasiya Kobrina, Albert Magohe, Samantha Leigh, Christin Ealer, Abigail Fellows, Catherine Reike, Enica Massawe and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Jeff JosephDepartment of Quantitative Biomedical Sciences, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Christopher NiemczakDepartment of Quantitative Biomedical Sciences, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Jonathan LichtensteinDepartment of Psychiatry, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA.
Anastasiya KobrinaSpace Medicine Innovations Laboratory, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Albert MagoheMuhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Samantha LeighSpace Medicine Innovations Laboratory, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Christin EalerSpace Medicine Innovations Laboratory, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Abigail FellowsSpace Medicine Innovations Laboratory, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Catherine ReikeSpace Medicine Innovations Laboratory, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Enica MassaweMuhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Jiang GuiDepartment of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Jay C BuckeyDepartment of Quantitative Biomedical Sciences, Geisel School of Medicine at Dartmouth, Hanover, NH, USA. Jay.C.Buckey.Jr@dartmouth.edu.
Dartmouth College · USDartmouth–Hitchcock Medical Center · USMuhimbili University of Health and Allied Sciences · TZ

Funding

Hearing impairment in HIV-infected and HIV/TB-coinfected individuals in TanzaniaR01DC009972 · NIDCD · DARTMOUTH COLLEGE · PI BUCKEY, JAY C · 2010 to 2019
$6.2M
Novel pediatric neurocognitive screening using central auditory testsR01HD095277 · NICHD · DARTMOUTH COLLEGE · PI JAY C BUCKEY · 2018 to 2026
$5.9M
NICHD NIH HHS R01 HD095277NIDCD NIH HHS R01 DC009972NIH HHS 5R01DC009972
6 · The paper itself

Abstract

Tests of the brain's ability to process complex sounds (central auditory tests) correlate with overall measures of neurocognitive performance. In the low- middle-income countries where resources to conduct detailed cognitive testing is limited, tests that assess the central auditory system may provide a novel and useful way to track neurocognitive performance. This could be particularly useful for children living with HIV (CLWH). To evaluate this, we administered central auditory tests to CLWH and children living without HIV and examined whether central auditory tests given early in a child's life could predict later neurocognitive performance. We used a machine learning technique to incorporate factors known to affect performance on neurocognitive tests, such as education. The results show that central auditory tests are useful predictors of neurocognitive performance and perform as well or in some cases better than factors such as education. Central auditory tests may offer an objective way to track neurocognitive performance in CLWH.

Indexed as

Hearing TestsHIV InfectionsChildEducational StatusHumansNeuropsychological Tests

Identifiers

PMID38302516
PMCPMC10834399
OpenAlexW4391451007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.