ArticleNature communications2024
Brain asymmetries from mid- to late life and hemispheric brain age.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 37 citations in OpenAlex.
- Arachidonic and docosahexaenoic acid supplementation affects white matter microstructure in preterm infants.Brain communications · 2026Trial
- Regional Brain Volume Variation Across Adulthood: A Cross-Sectional MRI Analysis of Age, Sex, and Hemispheric Asymmetry.Life (Basel, Switzerland) · 2026Article
- Invisible neuronal damage in stroke-free, asymptomatic chronic middle cerebral artery occlusion: evidence from soma and neurite density imaging.European radiology · 2026Article
- Variations of global brain asymmetry are associated with aging and related diseases.Science advances · 2026Article
- Women's reproductive factors predict local brain aging profiles mapped using deep neural networks.GeroScience · 2026Article
- Brain age gradients as intermediate phenotypes linking plasma p-tau217 to cognition in community-dwelling older adults.NPJ dementia · 2026Article
- Deep learning-based brain age predicts stroke recurrence in acute ischemic cerebrovascular disease.NPJ digital medicine · 2025Article
- No causal links between estradiol and female's brain and mental health using Mendelian randomization.Nature communications · 2025Article
- Multimodal predictors of disability progression and processing speed decline in relapsing-remitting multiple sclerosis.Scientific reports · 2025Article
- DunedinPACNI estimates the longitudinal Pace of Aging from a single brain image to track health and disease.Nature aging · 2025Article
- Charting structural brain asymmetry across the human lifespan.bioRxiv : the preprint server for biology · 2025Article
- Brain Aging in Patients With Cardiovascular Disease From the UK Biobank.Human brain mapping · 2025Article
- An estimate of the longitudinal pace of aging from a single brain scan predicts dementia conversion, morbidity, and mortality.bioRxiv : the preprint server for biology · 2025Article
- Cross-Sectional Brain Age Assessments Are Limited in Predicting Future Brain Change.Human brain mapping · 2025Article
- Decomposing the effect of normal aging and Alzheimer's disease in brain morphological changes via learned aging templates.Scientific reports · 2025Article
- Altered asymmetry of amygdala volume mediates food addiction and weight gain.Journal of behavioral addictions · 2025Article
- Learning-based inference of longitudinal image changes: Applications in embryo development, wound healing, and aging brain.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The Balance in the Head: How Developmental Factors Explain Relationships Between Brain Asymmetries and Mental Diseases.Brain sciences · 2025Review
- Feasibility of brain intra-axonal microstructure imaging with ultrahigh B-encoding using MAGNUS ultra-high-performance gradients.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Predicting brain age for veterans with traumatic brain injuries and healthy controls: an exploratory analysis.Frontiers in aging neuroscience · 2025Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The human brain demonstrates structural and functional asymmetries which have implications for ageing and mental and neurological disease development. We used a set of magnetic resonance imaging (MRI) metrics derived from structural and diffusion MRI data in N=48,040 UK Biobank participants to evaluate age-related differences in brain asymmetry. Most regional grey and white matter metrics presented asymmetry, which were higher later in life. Informed by these results, we conducted hemispheric brain age (HBA) predictions from left/right multimodal MRI metrics. HBA was concordant to conventional brain age predictions, using metrics from both hemispheres, but offers a supplemental general marker of brain asymmetry when setting left/right HBA into relationship with each other. In contrast to WM brain asymmetries, left/right discrepancies in HBA are lower at higher ages. Our findings outline various sex-specific differences, particularly important for brain age estimates, and the value of further investigating the role of brain asymmetries in brain ageing and disease development.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.