Evidence map›Paper›PMID 38302487›Full record

ArticleScientific data2024

A clinical microscopy dataset to develop a deep learning diagnostic test for urinary tract infection.

Natasha Liou, Trina De, Adrian Urbanski, Catherine Chieng, Qingyang Kong, Anna L David, Rajvinder Khasriya, Artur Yakimovich, Harry Horsley

Abstract readDataset
In one paragraph

Article in Scientific data, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Natasha LiouBladder Infection and Immunity Group (BIIG), UCL Centre for Kidney & Bladder Health, Division of Medicine, University College London, Royal Free Hospital Campus, London, UK.ORCID 0000-0002-5644-2604
Trina DeCenter for Advanced Systems Understanding (CASUS), Görlitz, Germany.
Adrian UrbanskiCenter for Advanced Systems Understanding (CASUS), Görlitz, Germany.ORCID 0009-0008-6619-3665
Catherine ChiengBladder Infection and Immunity Group (BIIG), UCL Centre for Kidney & Bladder Health, Division of Medicine, University College London, Royal Free Hospital Campus, London, UK.ORCID 0000-0001-8414-9969
Qingyang KongBladder Infection and Immunity Group (BIIG), UCL Centre for Kidney & Bladder Health, Division of Medicine, University College London, Royal Free Hospital Campus, London, UK.
Anna L DavidUCL EGA Institute for Women's Health, Faculty of Population Health Sciences, University College London, London, UK.ORCID 0000-0002-0199-6140
Rajvinder KhasriyaBladder Infection and Immunity Group (BIIG), UCL Centre for Kidney & Bladder Health, Division of Medicine, University College London, Royal Free Hospital Campus, London, UK.
Artur YakimovichBladder Infection and Immunity Group (BIIG), UCL Centre for Kidney & Bladder Health, Division of Medicine, University College London, Royal Free Hospital Campus, London, UK. a.yakimovich@hzdr.de.ORCID 0000-0003-2458-4904
Harry HorsleyBladder Infection and Immunity Group (BIIG), UCL Centre for Kidney & Bladder Health, Division of Medicine, University College London, Royal Free Hospital Campus, London, UK. h.horsley@ucl.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary tract infection (UTI) is a common disorder. Its diagnosis can be made by microscopic examination of voided urine for markers of infection. This manual technique is technically difficult, time-consuming and prone to inter-observer errors. The application of computer vision to this domain has been slow due to the lack of a clinical image dataset from UTI patients. We present an open dataset containing 300 images and 3,562 manually annotated urinary cells labelled into seven classes of clinically significant cell types. It is an enriched dataset acquired from the unstained and untreated urine of patients with symptomatic UTI using a simple imaging system. We demonstrate that this dataset can be used to train a Patch U-Net, a novel deep learning architecture with a random patch generator to recognise urinary cells. Our hope is, with this dataset, UTI diagnosis will be made possible in nearly all clinical settings by using a simple imaging system which leverages advanced machine learning techniques.

Indexed as

Deep LearningUrinary Tract InfectionsDiagnostic Tests, RoutineHumansMachine LearningMicroscopy

Identifiers

PMID38302487
PMCPMC10834944

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.