Evidence map›Paper›PMID 38302192›Full record

ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2024

Incidence and patterns of atrial fibrillation after catheter ablation of typical atrial flutter-the FLUTFIB study.

Philipp Attanasio, Tabea Budde, Paul Kamieniarz, Verena Tscholl, Patrick Nagel, Sebastian Biewener, Abdul Parwani, Leif-Hendrik Boldt, Ulf Landmesser, Gerhard Hindricks and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Female sex-related stroke risk in patients with atrial flutter-comparison between CHA2DS2-VA and CHA2DS2-VASc scores.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  2. Atrial fibrillation after cavotricuspid isthmus ablation for isolated typical atrial flutter: contemporary insights from a large global federated research network.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
  3. Intracardiac echocardiography-derived cavotricuspid isthmus morphology score for estimating procedural complexity in typical atrial flutter.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
    Article
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  7. Impact of the presence of sinus rhythm during cavotricuspid isthmus ablation for atrial flutter on the incidence of future new-onset atrial fibrillation: insights from an international multi-centre registry.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Philipp AttanasioDeutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin Hindenburgdamm 30, 12203 Berlin, Germany.ORCID 0000-0002-6559-7499
Tabea BuddeDeutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin Hindenburgdamm 30, 12203 Berlin, Germany.
Paul KamieniarzDeutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin Hindenburgdamm 30, 12203 Berlin, Germany.ORCID 0000-0002-3565-5790
Verena TschollDeutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin Hindenburgdamm 30, 12203 Berlin, Germany.ORCID 0000-0003-2748-2540
Patrick NagelDeutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin Hindenburgdamm 30, 12203 Berlin, Germany.
Sebastian BiewenerDeutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin Hindenburgdamm 30, 12203 Berlin, Germany.
Abdul ParwaniDeutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin, Augustenburger Platz 1, Berlin, Germany.ORCID 0000-0003-2043-7050
Leif-Hendrik BoldtDeutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin, Augustenburger Platz 1, Berlin, Germany.ORCID 0000-0002-3320-0880
Ulf LandmesserDeutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin Hindenburgdamm 30, 12203 Berlin, Germany.ORCID 0000-0002-0214-3203
Gerhard HindricksDeutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin, Charitéplatz 1, 10117 Berlin, Germany.ORCID 0000-0002-0132-0773
Martin HuemerDeutsches Herzzentrum der Charité, Klinik für Kardiologie, Angiologie und Intensivmedizin Hindenburgdamm 30, 12203 Berlin, Germany.
Deutsches Herzzentrum der Charité · DE

Funding

Abbott Medical
6 · The paper itself

Abstract

aimsIn patients with atrial flutter (AFL), ablation of the cavotricuspid isthmus (CTI) is a highly effective procedure to prevent AFL recurrence, but atrial fibrillation (AF) may occur during follow-up. The presented FLUTFIB study was designed to identify the exact incidence, duration, timely occurrence, and associated symptoms of AF after CTI ablation using continuous cardiac monitoring via implantable loop recorders. METHODS AND

resultsOne hundred patients with AFL without prior AF diagnosis were included after CTI ablation (mean age 69.7 ± 9.7 years, 18% female) and received an implantable loop recorder for AF detection. After a median follow-up of 24 months 77 patients (77%) were diagnosed with AF episodes. Median time to first AF occurrence was 180 (43-298) days. Episodes lasted longer than 1 h in most patients (45/77, 58%). Forty patients (52%) had AF-associated symptoms.Patients with and without AF development showed similar baseline characteristics and neither HATCH- nor CHA2DS2-VASc scores were predictive of future AF episodes. Oral anticoagulation (OAC) was stopped during FU in 32 patients (32%) and was re-initiated after AF detection in 15 patients (15%). No strokes or transient ischaemic attack episodes were observed during follow-up.

conclusionThis study represents the largest investigation using implantable loop recorders (ILRs) to detect AF after AFL ablation and shows a high incidence of AF episodes, most of them being asymptomatic and lasting longer than 1 h. In anticipation of trials determining the duration of AF episodes that should trigger OAC initiation, these results will help to guide anticoagulation management after CTI ablation.

Indexed as

Atrial FibrillationAtrial FlutterCatheter AblationAgedAnticoagulantsFemaleHumansIncidenceMaleMiddle AgedTreatment OutcomeAnticoagulantsAblationAtrial fibrillationAtrial flutterImplantable loop recorderOral anticoagulation

Identifiers

PMID38302192
PMCPMC10834233
OpenAlexW4391463592

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.