Functional Variants in MicroRNAs (rs895819, rs11614913 and rs2910164) Are Associated with Susceptibility and Clinicopathological Features in Mexican Patients with Colorectal Cancer.
Article in Archives of Iranian medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
11 authors at 3 institutions in 1 country.
Yuri Giovanna Vanessa Trujillo-FernándezMolecular Medicine Division, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, México.ORCID 0000-0002-9695-9771
Carmen Yzabal-BarbedilloMolecular Medicine Division, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, México.
Anilú Margarita Saucedo-SarinañaDepartment of Devices and Systems I, Facultad de Medicina. Decanato Ciencias de la Salud, Universidad Autónoma de Guadalajara (UAG). Zapopan, Jalisco, México.ORCID 0000-0003-4097-8671
César de Jesús Tovar-JácomeMolecular Medicine Division, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, México.
Miriam Yadira Godínez-RodríguezMolecular Medicine Division, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, México.
Patricio Barros-NúñezDoctorado en Genética Humana, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Jalisco, México.ORCID 0000-0002-6607-5553
Martha Patricia Gallegos-ArreolaGenetic Division, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, México.ORCID 0000-0003-4539-1693
Clara Ibet Juárez-VázquezDepartment of Devices and Systems I, Facultad de Medicina. Decanato Ciencias de la Salud, Universidad Autónoma de Guadalajara (UAG). Zapopan, Jalisco, México.
Tomás Daniel Pineda-RazoMedical Oncology Service, Hospital de Especialidades, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, México.ORCID 0000-0002-6757-731X
María Eugenia Marín-ContrerasGastroenterology Service, Hospital de Especialidades, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, México.ORCID 0000-0002-8352-236X
Mónica Alejandra Rosales-ReynosoMolecular Medicine Division, Centro de Investigación Biomédica de Occidente, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, México.ORCID 0000-0003-0387-4996
Mexican Social Security Institute · MXUniversidad Autónoma de Guadalajara · MXUniversidad de Guadalajara · MX
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
backgroundmiRNAs are non-coding RNAs participating actively in the post-translational regulation of oncogenes, tumor suppressor, and DNA repair genes implicated in colorectal cancer (CRC). This study aims to examine the association of the variants
methodsDNA samples from 183 patients and 186 healthy Mexican subjects were analyzed. Variants were identified by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) methodology. Association was calculated by the odds ratio (OR) and adjusted by the Bonferroni test.
resultsPatients carrying the G/G genotype of the rs895819 variant in the
conclusionOur results reveal that the rs895819 variant in
Indexed as
Colorectal NeoplasmsMicroRNAsCase-Control StudiesGenetic Predisposition to DiseaseGenotypeHumansPolymorphism, Single NucleotideMicroRNAsMIRN146 microRNA, humanMIRN196 microRNA, humanMIRN27 microRNA, humanCancer RiskColorectal cancermiR-146amiR-196a2miR-27aTNM stageTumor location
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Functional Variants in MicroRNAs (rs895819, rs11614913 and rs2910164) Are Associated with Susceptibility and Clinicopathological Features in Mexican Patients with Colorectal Cancer. · full record | OpenQuestion