Evidence map›Paper›PMID 38300918›Full record

ArticlePloS one2024

Spatial summation of pain is associated with pain expectations: Results from a home-based paradigm.

Jakub Nastaj, Jacek Skalski, Aleksandra Budzisz, Tibor M Szikszay, Sylwia Swoboda, Weronika Kowalska, Daria Nowak, Edyta Zbroja, Natalia Kruszyna, Marta Jakubińska and 5 more

Abstract read
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In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jakub NastajLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.
Jacek SkalskiLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.ORCID 0000-0001-6645-6906
Aleksandra BudziszLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.ORCID 0000-0002-6975-2644
Tibor M SzikszayInstitute of Health Sciences, Department of Physiotherapy, Pain & Exercise Research Lübeck, Universität zu Lübeck, Lübeck, Germany.
Sylwia SwobodaLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.
Weronika KowalskaLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.
Daria NowakLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.
Edyta ZbrojaLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.
Natalia KruszynaLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.
Marta JakubińskaLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.
Dominika GrygnyLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.
Romuald PolczykInstitute of Psychology, Jagiellonian University, Kraków, Poland.
Andrzej MałeckiLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.
Kerstin LuedtkeInstitute of Health Sciences, Department of Physiotherapy, Pain & Exercise Research Lübeck, Universität zu Lübeck, Lübeck, Germany.
Wacław M AdamczykLaboratory of Pain Research, Institute of Physiotherapy and Health Science, The Jerzy Kukuczka Academy of Physical Education, Katowice, Poland.ORCID 0000-0001-8941-8355

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to reproduce the previously observed spatial summation of pain effect (SSp) using non-laboratory procedures and commercial equipment. An additional aim was to explore the association between expectations and SSp. The Cold Pressor Task (CPT) was used to induce SSp. Healthy participants (N = 68) immersed their non-dominant hands (divided into 5 segments) into cold water (CPT). Two conditions were used 1) gradual hand immersion (ascending condition) and 2) gradual hand withdrawal (descending condition). Pain intensity was measured on a Visual Analogue Scale (VAS). Psychological factors, such as the participants' expectations of pain intensity were also measured on a VAS. Results showed significant SSp (χ2(4) = 116.90, p < 0.001), reproduced with non-laboratory equipment in a home-based set-up. Furthermore, two novel findings were observed: i) there was a significant correlation between expectations and perceived pain, indicating a link between pain expectations and SSp, ii) spatial summation increased with the increase in duration exposure to the noxious stimulus (Wald χ2(8) = 80.80, p < 0.001). This study suggests that SSp is associated with pain expectations and can be formed by a mixture of excitatory and inhibitory mechanisms potentially driven by temporal characteristics of neural excitation. Moreover, this study proposes a new feasible way to induce SSp using a home-based set-up.

Indexed as

MotivationPainCold TemperatureHumansPain MeasurementPain Threshold

Identifiers

PMID38300918
PMCPMC10833545

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.