Evidence map›Paper›PMID 38300871›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Cell lineage-guided mass spectrometry reveals increased energy metabolism and reactive oxygen species in the vertebrate organizer.

Aparna B Baxi, Jie Li, Vi M Quach, Leena R Pade, Sally A Moody, Peter Nemes

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Heterologous Expression of aJournal of fungi (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Aparna B BaxiDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742.
Jie LiDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742.ORCID 0000-0002-4282-4919
Vi M QuachDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742.
Leena R PadeDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742.
Sally A MoodyDepartment of Anatomy and Cell Biology, School of Medical and Health Sciences, The George Washington University, Washington, DC 20037.ORCID 0000-0003-4192-1087
Peter NemesDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742.ORCID 0000-0002-4704-4997
George Washington University · USUniversity of Maryland, College Park · US

Funding

Sub-Cellular Mass Spectrometry Discoveries: Metabolic Encoding of the Embryonic Body PlanR35GM124755 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI Peter Nemes · 2017 to 2026
$3.8M
NIGMS NIH HHS R35 GM124755
6 · The paper itself

Abstract

Molecular understanding of the vertebrate Organizer, a tissue center critical for inductive signaling during gastrulation, has so far been mostly limited to transcripts and a few proteins, the latter due to limitations in detection and sensitivity. The Spemann-Mangold Organizer (SMO) in the South African Clawed Frog (

Indexed as

Body PatterningProteomicsAnimalsCell LineageEnergy MetabolismGene Expression Regulation, DevelopmentalOrganizers, EmbryonicReactive Oxygen SpeciesTranscription FactorsXenopus laevisXenopus ProteinsReactive Oxygen SpeciesTranscription FactorsXenopus Proteinsmass spectrometrymetabolomicsproteomicsSpemann–Mangold OrganizerXenopus

Identifiers

PMID38300871
PMCPMC10861879
OpenAlexW4391423444

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.