Evidence map›Paper›PMID 38300481›Full record

ArticleObesity surgery2024

Prospective Monitoring of Small Intestinal Bacterial Overgrowth After Gastric Bypass: Clinical, Biological, and Gas Chromatographic Aspects.

Vincent Florent, Solen Dennetiere, Bulle Gaudrat, Severine Andrieux, Emmanuel Mulliez, Laurene Norberciak, Kathleen Jacquez

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02819037 (Modification of Digestive Flora After Gastric Bypass), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02819037 nacompletednot on this map

Modification of Digestive Flora After Gastric Bypass : Pilot Study on Microbial Overgrowth Using Gas Chromatography

TypeinterventionalSponsorLille Catholic UniversityRan2016 to 2022Enrolled51ConditionsGastric Bypass, Blind Loop Syndrome, Bacterial Overgrowth Syndrome, Chromatography, GasArmsgas chromatography, Stool analysis for detection of malabsorption
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Vincent FlorentDepartment of Nutrition, Arras General Hospital, Bd Besnier, 62000, Arras, France. vincent.florent@gh-artoisternois.fr.ORCID 0000-0002-6436-081X
Solen DennetiereDepartment of Nutrition, Arras General Hospital, Bd Besnier, 62000, Arras, France.
Bulle GaudratDepartment of Nutrition, Arras General Hospital, Bd Besnier, 62000, Arras, France.
Severine AndrieuxDepartment of Nutrition, Arras General Hospital, Bd Besnier, 62000, Arras, France.
Emmanuel MulliezDepartment of Nutrition, Douai General Hospital, 59500, Douai, France.
Laurene NorberciakDelegation for Clinical Research and Innovation, Biostatistics Unit, Group of Hospitals of the Catholic Institute of Lille, 59000, Lille, France.
Kathleen JacquezClinical Research Unit, Arras General Hospital, 62000, Arras, France.
Centre Hospitalier d'Arras · FRCentre Hospitalier de Douai · FRInserm · FRUniversité de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsObesity is a predisposing factor for small intestinal bacterial overgrowth (SIBO). The aim of this study was to prospectively evaluate the prevalence of SIBO as well as its clinical, biological, and nutritional aspects before and up to 24 months after a Roux-en-Y gastric bypass (RYGB) surgery. PATIENTS AND

methodsFifty-one patients (mean BMI 46.9 kg/m

resultsBefore surgery, we found a prevalence of 17.6% of SIBO (95% CI = [8.9%; 31.4%]). After RYGB, at the end of 24 months of follow-up, 89.5% of patients developed SIBO. Anal incontinence appeared to be very frequent after surgery, affecting 18.8% of our population 18 months after surgery. We observed positive steatorrhea after surgery with an average of 11.1 g of lipids/24 h despite a significant limitation of dietary lipids (p = 0.0282).

conclusionOur study corroborates data in the literature on the prevalence of SIBO in severe obesity patients. For the first time, we observed the sudden appearance of SIBO after RYGB, with a correlation between exhaled hydrogen on a breath test and lipid malabsorption on the fecalogram. As a result, these patients develop fatty diarrhea, with frequent fecal incontinence.

Indexed as

Gastric BypassObesity, MorbidSteatorrheaFemaleHumansLipidsMaleObesityProspective StudiesLipidsBreath testFecalogramRoux-en-Y gastric bypassSmall intestinal bacterial overgrowth

Identifiers

PMID38300481
OpenAlexW4391431696

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.