Evidence map›Paper›PMID 38300428›Full record

ArticleJournal of racial and ethnic health disparities2025

Regional and Demographic Disparities in Atrial Fibrillation Mortality in the USA.

Unoma Okoli, Ayobami S Ogunsola, Zahira Adeniyi, Aisha Abdulkadir, Susan M DeMetropolis, Eniola A Olatunji, Ibraheem M Karaye

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Article in Journal of racial and ethnic health disparities, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Trends in atrial fibrillation-related mortality among adults under 65 years in the USA.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Unoma OkoliDepartment of Medicine, Mount Auburn Hospital, Harvard Medical School, 330 Mount Auburn St, Cambridge, MA, 02138, USA. nonye.okoli1@gmail.com.ORCID 0000-0001-9705-7932
Ayobami S OgunsolaDepartment of Orthopedic Surgery, Wake Forest University School of Medicine, 475 Vine St, Winston-Salem, NC, 27101, USA.
Zahira AdeniyiDepartment of Population Health, Hofstra University, 106 Hofstra Dome, Hempstead, NY, 11549, USA.
Aisha AbdulkadirDepartment of Population Health, Hofstra University, 106 Hofstra Dome, Hempstead, NY, 11549, USA.
Susan M DeMetropolisDepartment of Speech, & Hearing Sciences, Hofstra University, Davison Hall 0106C, LanguageHempstead, NY, 11549, USA.
Eniola A OlatunjiDepartment of Health Policy & Management, Texas A&M University, 212 Adriance Lab Rd, College Station, TX, 77843-1266, USA.
Ibraheem M KarayeDepartment of Population Health, Hofstra University, 106 Hofstra Dome, Hempstead, NY, 11549, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the burden of atrial fibrillation/flutter (AF/AFL) in the USA, an assessment of contemporary mortality trends is scarce in the literature. This study aimed to assess the temporal trends in AF/AFL deaths among US adults by age, sex, race/ethnicity, and census region from 1999 to 2020.

methodsNational mortality data was abstracted from the National Center for Health Statistics to identify decedents whose underlying cause of death was cardiovascular disease and multiple cause of death, AF/AFL. Joinpoint regression assessed mortality trends, and we calculated the average percentage changes (APC) and average annual percentage changes in mortality rates. Results were presented as effect estimates and 95% confidence intervals (95% CI).

resultsBetween 1999 and 2020, 657,126 adults died from AF/AFL in the USA. Contemporary trends have worsened overall except among individuals from the Northeast region for whom the rates have remained stationary since 2015 (APC = 0.1; 95% CI, - 1.0, 1.1). Regional and demographic disparities were observed, with higher rates noted among younger persons below 65 years of age, women (APC = 2.1; 95% CI, 1.7, 2.5), and non-Hispanic Blacks (APC = 4.5; 95% CI, 3.9, 5.2).

conclusionsThe temporal trends in AF/AFL mortality in the USA have exhibited a worsening pattern in recent years, with regional and demographic disparities. Further investigations are warranted to explore the determinants of AF/AFL mortality in the US population and identify factors that may explain the observed differences. Understanding these factors will facilitate efforts to promote improved and equitable health outcomes for the population.

Indexed as

Atrial FibrillationHealth Status DisparitiesAdultAgedAged, 80 and overEthnicityFemaleHumansMaleMiddle AgedMortalityRacial GroupsUnited StatesAtrial fibrillationBurdenDeathsDisparitiesMortalityTrendsUSA

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.