Evidence map›Paper›PMID 38300359›Full record

ArticleJournal of materials science. Materials in medicine2024

Synthesis, and evaluation of photophysical properties of a potential DPP-derived photosensitizer for photodynamic therapy with D-A-D architecture.

Vanessa Escalona Hernández, Itzia Irene Padilla-Martínez, Rosa Angeles Vázquez García, María Aurora Veloz Rodríguez, Oscar Javier Hernández-Ortiz

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of materials science. Materials in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Biopolymeric stabilization of photonic nanoaggregates using amaranth starch: toward applications in bioimaging and photodynamic therapy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vanessa Escalona HernándezÁrea Académica de Ciencias de la Tierra y Materiales, Carretera Pachuca-Tulancingo Km, Universidad Autónoma del Estado de Hidalgo (UAEH), 4.5.C.P. 42184. Ciudad del Conocimiento, Mineral de la Reforma, Hgo, México.
Itzia Irene Padilla-MartínezLaboratorio de Química Supramolecular y Nanociencias de la Unidad Profesional Interdisciplinaria de Biotecnología del Instituto Politécnico Nacional, Av. Acueducto s/n Barrio la laguna Ticomán, Ciudad de México, 07340, México. itzia20042000@yahoo.com.mx.
Rosa Angeles Vázquez GarcíaÁrea Académica de Ciencias de la Tierra y Materiales, Carretera Pachuca-Tulancingo Km, Universidad Autónoma del Estado de Hidalgo (UAEH), 4.5.C.P. 42184. Ciudad del Conocimiento, Mineral de la Reforma, Hgo, México.
María Aurora Veloz RodríguezÁrea Académica de Ciencias de la Tierra y Materiales, Carretera Pachuca-Tulancingo Km, Universidad Autónoma del Estado de Hidalgo (UAEH), 4.5.C.P. 42184. Ciudad del Conocimiento, Mineral de la Reforma, Hgo, México.
Oscar Javier Hernández-OrtizÁrea Académica de Ciencias de la Tierra y Materiales, Carretera Pachuca-Tulancingo Km, Universidad Autónoma del Estado de Hidalgo (UAEH), 4.5.C.P. 42184. Ciudad del Conocimiento, Mineral de la Reforma, Hgo, México. ojavier.hdez@gmail.com.ORCID http://orcid.org/0000-0002-5805-9035
Universidad Autónoma del Estado de Hidalgo · MXInstituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study of a macromolecule derived from DPP and triphenylamine, (DPP-BisTPA) by computational chemistry, its synthesis by direct arylation, optical characterization (UV-Vis and fluorescence) and electrochemistry (cyclic voltammetry), as well as its evaluation as a generator of reactive oxygen species indirectly, through the degradation of uric acid. The results obtained by DFT using B3LYP/6-31G (d, p) and TD-DFT using CAM-B3LYP/6-31G (d, p) reveal values of energy levels of the first singlet and triplet excited state that indicate a possible intersystem crossover and the possible generation of reactive oxygen species by a type I mechanism. The compound presents an absorption region within the phototherapeutic window. The electrochemical bandgap is 1.64 eV which suggests a behavior as a semiconductor. DPP-BisTPa were processed as hemispherical nanoparticles with a size around 100 nm, and NPOs were evaluated as a photosensitizer with a ROS generation yield of 4% using a photodynamic therapy flashlight as the light source.

Indexed as

PhotochemotherapyPhotosensitizing AgentsAminesElectrochemistryReactive Oxygen SpeciesAminesPhotosensitizing AgentsReactive Oxygen Species

Identifiers

PMID38300359
PMCPMC10834609
OpenAlexW4391439461

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.