Evidence map›Paper›PMID 38300356›Full record

ArticleJournal of cardiovascular translational research2024

FLAVOUR Study: FLow profiles And postoperative VasOplegia after continUous-flow left ventriculaR assist device implantation.

Bas J Kersten, Lieke Numan, Marnix M van der Schoot, Michel de Jong, Faiz Ramjankhan, Emmeke Aarts, Marish I F J Oerlemans, Linda W van Laake, Eric E C de Waal

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiovascular translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bas J Kersten *Department of Anesthesiology, University Medical Center Utrecht, Post Office Box 85500, 3508, Utrecht, GA, Netherlands.
Lieke Numan *Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Marnix M van der SchootDepartment of Anesthesiology, Leiden University Medical Center, Leiden, Netherlands.
Michel de JongHeartbeat Perfusion, University Medical Center Utrecht, Utrecht, Netherlands.
Faiz RamjankhanDepartment of Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, Netherlands.
Emmeke AartsDepartment of Methodology and Statistics, Utrecht University, Utrecht, Netherlands.
Marish I F J OerlemansDepartment of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Linda W van LaakeDepartment of Cardiology, University Medical Center Utrecht, Utrecht, Netherlands.
Eric E C de WaalDepartment of Anesthesiology, University Medical Center Utrecht, Post Office Box 85500, 3508, Utrecht, GA, Netherlands. e.e.c.dewaal@umcutrecht.nl.ORCID 0000-0003-1419-5817

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims to associate the incidence of postoperative vasoplegia and short-term survival to the implantation of various left ventricular assist devices differing in hemocompatibility and flow profiles. The overall incidence of vasoplegia was 25.3% (73/289 patients) and 30.3% (37/122), 25.0% (18/72), and 18.9% (18/95) in the axial flow (AXF), centrifugal flow (CF), and centrifugal flow with artificial pulse (CFAP) group, respectively. Vasoplegia was associated with longer intensive care (ICU) and hospital length of stay (LOS) and mortality. ICU and in-hospital LOS and 1-year mortality were the lowest in the CFAP group. Post hoc analysis resulted in a p-value of 0.43 between AXF and CF; 0.35 between CF and CFAP; and 0.06 between AXF and CFAP. Although there is a trend in diminished incidence of vasoplegia, pooled logistic regression using flow profile and variables that remained after feature selection showed that flow profile was not an independent predictor for postoperative vasoplegia.

Indexed as

Heart-Assist DevicesLength of StayProsthesis DesignVasoplegiaVentricular Function, LeftAdultAgedFemaleHeart FailureHospital MortalityHumansIncidenceMaleMiddle AgedProsthesis ImplantationRetrospective StudiesAxial flowCardiac vasoplegia syndromeCentrifugal flowCentrifugal flow with artificial pulseContinuous-flow left ventricular assist deviceFlow profileMorbidityMortalityOutcomes

Identifiers

PMID38300356
PMCPMC11052811

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.