Evidence map›Paper›PMID 38299857›Full record

ArticleJournal of bacteriology2024

Mechanism of 2'-fucosyllactose degradation by human-associated

Loren Padilla, Ashwana D Fricker, Estefani Luna, Biswa Choudhury, Elizabeth R Hughes, Maria E Panzetta, Raphael H Valdivia, Gilberto E Flores

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Akkermansia muciniphila MucNature communications · 2025
    Article
  8. The Biology ofAnnual review of microbiology · 2025
    Review
  9. Review
  10. Review
  11. Pangenomic analysis identifies correlations betweenMicrobiome research reports · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Loren Padilla *Department of Biology, California State University, Northridge, California, USA.
Ashwana D Fricker *Department of Biology, California State University, Northridge, California, USA.ORCID 0000-0002-3806-7695
Estefani LunaDepartment of Biology, California State University, Northridge, California, USA.
Biswa ChoudhuryGlycoAnalytics Core, UC San Diego, Health Sciences, La Jolla, California, USA.
Elizabeth R HughesDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, North Carolina, USA.
Maria E PanzettaDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, North Carolina, USA.
Raphael H ValdiviaDepartment of Integrative Immunobiology, Duke University School of Medicine, Durham, North Carolina, USA.
Gilberto E FloresDepartment of Biology, California State University, Northridge, California, USA.ORCID 0000-0002-3338-611X
California State University, Northridge · USDuke University · USUC San Diego Health System · US

Funding

Mechanisms of mucin binding and acquisition by AkkermansiaR01AI142376 · NIAID · DUKE UNIVERSITY · PI Raphael H Valdivia · 2018 to 2026
$2.9M
Mechanisms and consequences of human milk oligosaccharide growth and bile stress across diverse strains of the potential therapeutic bacterium, Akkermansia muciniphila.SC1GM136546 · NIGMS · CALIFORNIA STATE UNIVERSITY NORTHRIDGE · PI FLORES, GILBERTO · 2020 to 2023
$1.5M
NIAID NIH HHS R01 AI142376NIGMS NIH HHS SC1 GM136546
6 · The paper itself

Abstract

Among the first microorganisms to colonize the human gut of breastfed infants are bacteria capable of fermenting human milk oligosaccharides (HMOs). One of the most abundant HMOs, 2'-fucosyllactose (2'-FL), may specifically drive bacterial colonization of the intestine. Recently, differential growth has been observed across multiple species of

Indexed as

Akkermansiaalpha-L-FucosidaseTrisaccharidesbeta-GalactosidaseHumansInfantOligosaccharidesPhylogeny2'-fucosyllactosealpha-L-Fucosidasebeta-GalactosidaseOligosaccharidesTrisaccharides2’-FLAkkermansiaglycoside hydrolaseHMOstranscriptomics

Identifiers

PMID38299857
PMCPMC10886448
OpenAlexW4391449955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.