Evidence map›Paper›PMID 38299836›Full record

ReviewMicrobiology and molecular biology reviews : MMBR2024

The intersection of host

Sarah Ewald, Azadeh Nasuhidehnavi, Tzu-Yu Feng, Mahbobeh Lesani, Laura-Isobel McCall

Abstract readReview
In one paragraph

Review in Microbiology and molecular biology reviews : MMBR, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sarah EwaldDepartment of Microbiology, Immunology, and Cancer Biology at the Carter Immunology Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA.ORCID 0000-0002-5327-7578
Azadeh NasuhidehnaviDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma, USA.
Tzu-Yu FengDepartment of Microbiology, Immunology, and Cancer Biology at the Carter Immunology Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Mahbobeh LesaniDepartment of Microbiology and Plant Biology, University of Oklahoma, Norman, Oklahoma, USA.
Laura-Isobel McCallDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma, USA.ORCID 0000-0002-1243-8953

Funding

Mechanisms of myocarditis and progressive cardiac fibrosis in chronic Trypanosoma cruzi infection.R01AI168038 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI Kathryn Marie Jones · 2022 to 2026
$3.8M
Innate Inflammatory Control of CachexiaR35GM138381 · NIGMS · UNIVERSITY OF VIRGINIA · PI Sarah E. Ewald · 2020 to 2026
$2.9M
UC San Diego RAPID Faculty Development Program in Infectious DiseasesR25AI147376 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ADRIANA H TREMOULET, Joann Trejo · 2020 to 2026
$2.5M
Deciphering the mechanism of action of carnitine, a novel treatment for chronic Chagas diseaseR01AI170605 · NIAID · UNIVERSITY OF OKLAHOMA · PI Laura-Isobel McCall · 2022 to 2026
$2.3M
Small molecule biomarkers of cardiac Chagas disease progressionR21AI156669 · NIAID · UNIVERSITY OF OKLAHOMA · PI BOWMAN, NATALIE MCCARTER, GILMAN, ROBERT H · 2021 to 2022
$458k
Proteomic interrogation of the parasite vacuole using autoSTOMPR21AI156153 · NIAID · UNIVERSITY OF VIRGINIA · PI EWALD, SARAH E. · 2021 to 2022
$444k
NIAID NIH HHS R01 AI168038NIAID NIH HHS R01 AI170605NIAID NIH HHS R21 AI156153NIAID NIH HHS R21 AI156669NIAID NIH HHS R25 AI147376NIGMS NIH HHS R35 GM138381
6 · The paper itself

Abstract

SUMMARYProtozoan parasite infection dramatically alters host metabolism, driven by immunological demand and parasite manipulation strategies. Immunometabolic checkpoints are often exploited by kinetoplastid and protozoan parasites to establish chronic infection, which can significantly impair host metabolic homeostasis. The recent growth of tools to analyze metabolism is expanding our understanding of these questions. Here, we review and contrast host metabolic alterations that occur

Indexed as

CryptosporidiosisCryptosporidiumParasitesPlasmodiumToxoplasmaAnimalsHumansImmunityProtozoan ProteinsProtozoan ProteinsapicomplexanCryptosporidiumhost-parasite relationshipimmunitykinetoplastidaLeishmaniametabolismPlasmodiumToxoplasma gondiiTrypanosoma

Identifiers

PMID38299836
PMCPMC10966954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.