Evidence map›Paper›PMID 38299598›Full record

ArticleThe American journal of gastroenterology2024

Forecasting the Incidence and Prevalence of Inflammatory Bowel Disease: A Canadian Nationwide Analysis.

Stephanie Coward, Eric I Benchimol, Charles N Bernstein, Antonio Avina-Zubieta, Alain Bitton, Matthew W Carroll, Yungsong Cui, Frank Hoentjen, Lindsay Hracs, Kevan Jacobson and 16 more

Abstract read
In one paragraph

Article in The American journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Nationalization of clinical care pathways for inflammatory bowel disease management in Canada.Journal of the Canadian Association of Gastroenterology · 2026
    Article
  9. Single-center experience of the Crohn's disease exclusion diet in the United States: A retrospective study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026
    Article
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Stephanie CowardDivision of Gastroenterology and Hepatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-0675-7226
Eric I BenchimolSickKids Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children (SickKids), Toronto, Ontario, Canada.ORCID 0000-0001-8855-3598
Charles N BernsteinDepartment of Medicine, and the University of Manitoba IBD Clinical and Research Centre, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Antonio Avina-ZubietaDivision of Rheumatology, University of British Columbia, Vancouver, British Columbia, Canada.
Alain BittonDivision of Gastroenterology and Hepatology, McGill University and McGill University Health Centre, Montreal, Quebec, Canada.
Matthew W CarrollDivision of Gastroenterology and Nutrition, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0003-4237-0512
Yungsong CuiAtlantic PATH, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0001-5656-4321
Frank HoentjenDivision of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Canada.ORCID 0000-0001-5314-4452
Lindsay HracsDivision of Gastroenterology and Hepatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Kevan JacobsonDepartment of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Faculty of Medicine, British Columbia Children's Hospital and British Columbia Children Hospital Research Institute, Vancouver, British Columbia, Canada.ORCID 0000-0001-7269-8557
Jennifer L JonesDepartment of Medicine & Clinical Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0002-6380-6728
James KingDivision of Gastroenterology and Hepatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-1332-3610
M Ellen KuenzigChild Health Evaluative Sciences, SickKids Research Institute, Toronto, Ontario, Canada.ORCID 0000-0002-3984-8426
Na LuArthritis Research Canada, Vancouver, British Columbia, Canada.
Wael El-MataryDepartment of Pediatrics, and the Children's Hospital Research Institute of Manitoba, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.
Sanjay K MurthyThe Ottawa Hospital IBD Centre and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.ORCID 0000-0002-0128-7897
Zoann NugentUniversity of Manitoba, Winnipeg, Manitoba, Canada.
Anthony R OtleyDepartment of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0002-7371-9302
Remo PanaccioneDivision of Gastroenterology and Hepatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Juan Nicolás Peña-SánchezDepartment of Community Health & Epidemiology, University of Saskatchewan, Saskatoon, Canada.ORCID 0000-0002-4653-525
Harminder SinghDepartments of Medicine and Community Health Sciences, the University of Manitoba IBD Clinical and Research Centre, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada.ORCID 0000-0002-9354-2356
Laura E TargownikDivision of Gastroenterology and Hepatology, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-4366-9076
Dominic WhiteNewfoundland and Labrador Centre for Health Information, St. John's, Newfoundland, Canada.ORCID 0009-0005-3503-4934
Joseph W WindsorDivision of Gastroenterology and Hepatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-7539-9103
Gilaad G KaplanDivision of Gastroenterology and Hepatology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0003-2719-0556
Canadian Gastro-Intestinal Epidemiology Consortium (CanGIEC)

Funding

CIHR PJT-162393Leona M. and Harry B. Helmsley Charitable Trust G-2108-04777
6 · The paper itself

Abstract

introductionCanada has a high burden of inflammatory bowel disease (IBD). Historical trends of IBD incidence and prevalence were analyzed to forecast the Canadian burden over the next decade.

methodsPopulation-based surveillance cohorts in 8 provinces derived from health administrative data assessed the national incidence (2007-2014) and prevalence (2002-2014) of IBD. Autoregressive integrated moving average models were used to forecast incidence and prevalence, stratified by age, with 95% prediction intervals (PI), to 2035. The average annual percentage change (AAPC) with 95% confidence interval (CI) was calculated for the forecasted incidence and prevalence.

resultsThe national incidence of IBD is estimated to be 29.9 per 100,000 (95% PI 28.3-31.5) in 2023. With a stable AAPC of 0.36% (95% CI -0.05 to 0.72), the incidence of IBD is forecasted to be 31.2 per 100,000 (95% PI 28.1-34.3) in 2035. The incidence in pediatric patients (younger than 18 years) is increasing (AAPC 1.27%; 95% CI 0.82-1.67), but it is stable in adults (AAPC 0.26%; 95% CI -0.42 to 0.82). The prevalence of IBD in Canada was 843 per 100,000 (95% PI 716-735) in 2023 and is expected to steadily climb (AAPC 2.43%; 95% CI 2.32-2.54) to 1,098 per 100,000 (95% PI 1,068-1,127) by 2035. The highest prevalence is in seniors with IBD (1,174 per 100,000 in 2023; AAPC 2.78%; 95% CI 2.75-2.81). DISCUSSION: Over the next decade, the Canadian health care systems will contend with the juxtaposition of rising incidence of pediatric IBD and a rising prevalence of overall IBD driven by the aging population.

Indexed as

ForecastingInflammatory Bowel DiseasesAdolescentAdultAgedAge DistributionCanadaChildChild, PreschoolFemaleHumansIncidenceMaleMiddle AgedPrevalenceYoung Adult

Identifiers

PMID38299598
PMCPMC11288393

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.