Evidence map›Paper›PMID 38299318›Full record

ArticleGut microbes

Z Krekhno, S E Woodward, A Serapio-Palacios, J Peña-Díaz, K M Moon, L J Foster, B B Finlay

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. mBio · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Z KrekhnoDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0002-3945-2114
S E WoodwardDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.
A Serapio-PalaciosDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.
J Peña-DíazDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.
K M MoonMichael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.
L J FosterMichael Smith Laboratories, University of British Columbia, Vancouver, BC, Canada.
B B FinlayDepartment of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0001-5303-6128
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infectious diarrheal diseases are the third leading cause of mortality in young children, many of which are driven by Gram-negative bacterial pathogens. To establish successful host infections these pathogens employ a plethora of virulence factors necessary to compete with the resident microbiota, and evade and subvert the host defenses. The type II secretion system (T2SS) is one such conserved molecular machine that allows for the delivery of effector proteins into the extracellular milieu. To explore the role of the T2SS during natural host infection, we used

Indexed as

Enterobacteriaceae InfectionsEnterohemorrhagic Escherichia coliGastrointestinal MicrobiomeType II Secretion SystemsAnimalsChildChild, PreschoolCitrobacter rodentiumHumansMiceVirulence FactorsType II Secretion SystemsVirulence Factorsattaching and effacing pathogenbacterial pathogenesisCitrobacter rodentiumenteric infectionhost-pathogen interactionsmucinmucosal invasionmucus degradationT2SStype II secretion system

Identifiers

PMID38299318
PMCPMC10841016
OpenAlexW4391447401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.