Evidence map›Paper›PMID 38299032›Full record

ArticleiScience2024

MIF modulates p38/ERK phosphorylation via MKP-1 induction in sarcoidosis.

Jaya Talreja, Changya Peng, Lobelia Samavati

Open access · goldAbstract read
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 6 citations in OpenAlex.

  1. DONSON links tumor-cell survival to MIF-associated macrophage remodeling in small cell lung cancer.Apoptosis : an international journal on programmed cell death · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jaya TalrejaDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University, School of Medicine and Detroit Medical Center, Detroit, MI 48201, USA.
Changya PengDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University, School of Medicine and Detroit Medical Center, Detroit, MI 48201, USA.
Lobelia SamavatiDepartment of Internal Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Wayne State University, School of Medicine and Detroit Medical Center, Detroit, MI 48201, USA.
Detroit Medical Center · USWayne State University · US

Funding

Role and Regulation of MKP-1 in SarcoidosisR01HL113508 · NHLBI · WAYNE STATE UNIVERSITY · PI SAMAVATI, LOBELIA · 2013 to 2017
$1.9M
A novel T7 phage display technology to detect sarcoidosis specific antigensR01HL150474 · NHLBI · WAYNE STATE UNIVERSITY · PI SAMAVATI, LOBELIA · 2020 to 2023
$1.8M
Diagnostic classifiers for sarcoidosis using a novel T7 phage display technologyR21HL148089 · NHLBI · WAYNE STATE UNIVERSITY · PI SAMAVATI, LOBELIA · 2019 to 2020
$231k
NHLBI NIH HHS R01 HL113508NHLBI NIH HHS R01 HL150474NHLBI NIH HHS R21 HL148089
6 · The paper itself

Abstract

Macrophage migration inhibitory factor (MIF) is a versatile cytokine that influences a variety of cellular processes important for immune regulation and tissue homeostasis. Sarcoidosis is a granulomatous disease characterized by extensive local inflammation and increased T helper cell mediated cytokines. We have shown that MIF has a modulatory role in cytokine networks in sarcoidosis. We investigated the effect of exogenous MIF on sarcoidosis alveolar macrophages (AMs), CD14

Indexed as

ImmunologyMolecular biology

Identifiers

PMID38299032
PMCPMC10829885
OpenAlexW4389720640

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.