Evidence map›Paper›PMID 38298822›Full record

ArticlePreventive medicine reports2024

Pairwise association of key lifestyle factors and risk of solid cancers - A prospective pooled multi-cohort register study.

Eira Roos, Sanna Heikkinen, Karri Seppä, Olli Pietiläinen, Heidi Ryynänen, Maarit Laaksonen, Teemu Roos, Paul Knekt, Satu Männistö, Tommi Härkänen and 6 more

Open access · goldAbstract read
In one paragraph

Article in Preventive medicine reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Cancer disparities: an extensive review.Ecancermedicalscience · 2026
    Review
  3. Exploring behavioural motivations of treatment refusal in cancer: a Q-methodological approach.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  4. Exosomal ncRNAs in reproductive cancers†.Biology of reproduction · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Eira RoosDepartment of Public Health, University of Helsinki, Finland.
Sanna HeikkinenFinnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland.
Karri SeppäFinnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland.
Olli PietiläinenDepartment of Public Health, University of Helsinki, Finland.
Heidi RyynänenFinnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland.
Maarit LaaksonenDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
Teemu RoosDepartment of Computer Science, University of Helsinki, Finland.
Paul KnektDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
Satu MännistöDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
Tommi HärkänenDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
Pekka JousilahtiDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
Seppo KoskinenDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
Johan G ErikssonDepartment of Public Health and Welfare, Finnish Institute for Health and Welfare (THL), Helsinki, Finland.
Nea MalilaFinnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland.
Ossi RahkonenDepartment of Public Health, University of Helsinki, Finland.
Janne PitkäniemiFinnish Cancer Registry, Institute for Statistical and Epidemiological Cancer Research, Helsinki, Finland.
University of Helsinki · FIFinnish Institute for Health and Welfare · FIFinnish Cancer Registry · FIUNSW Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Smoking, alcohol consumption, obesity, and physical inactivity are key lifestyle risk factors for cancer. Previously these have been mostly examined singly or combined as an index, assuming independent and equivalent effects to cancer risk. The aim of our study was to systematically examine the joint pairwise and interactive effects of these lifestyle factors on the risk of a first solid primary cancer in a multi-cohort prospective setting. We used pooled data from seven Finnish health survey studies during 1972-2015, with 197,551 participants diagnosed with 16,373 solid malignant primary tumors during follow-up. Incidence of any cancer was analyzed separately without and with lung cancers using Poisson regression with main and interaction effects of key lifestyle factors. When excluding lung cancer, the highest risk of any cancer in men was observed for smokers with a BMI of ≥25 kg/m

Indexed as

Alcohol consumptionCancerLifestyle habitsObesityPhysical activitySmoking

Identifiers

PMID38298822
PMCPMC10828451
OpenAlexW4390823290

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.