Evidence map›Paper›PMID 38298588›Full record

ReviewNanoscale advances2024

Metallic nanostructure-based aptasensors for robust detection of proteins.

Navid Rabiee, Sepideh Ahmadi, Kamal Rahimizadeh, Suxiang Chen, Rakesh N Veedu

Abstract readReview
In one paragraph

Review in Nanoscale advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Novel and Extremely Sensitive NiAlMolecules (Basel, Switzerland) · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Navid RabieeCentre for Molecular Medicine and Innovative Therapeutics, Health Futures Institute, Murdoch University Perth WA 6150 Australia r.veedu@murdoch.edu.au.ORCID https://orcid.org/0000-0002-6945-8541
Sepideh AhmadiStudent Research Committee, Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences Tehran Iran.
Kamal RahimizadehCentre for Molecular Medicine and Innovative Therapeutics, Health Futures Institute, Murdoch University Perth WA 6150 Australia r.veedu@murdoch.edu.au.
Suxiang ChenCentre for Molecular Medicine and Innovative Therapeutics, Health Futures Institute, Murdoch University Perth WA 6150 Australia r.veedu@murdoch.edu.au.
Rakesh N VeeduCentre for Molecular Medicine and Innovative Therapeutics, Health Futures Institute, Murdoch University Perth WA 6150 Australia r.veedu@murdoch.edu.au.ORCID https://orcid.org/0000-0003-2192-9532

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a significant need for fast, cost-effective, and highly sensitive protein target detection, particularly in the fields of food, environmental monitoring, and healthcare. The integration of high-affinity aptamers with metal-based nanomaterials has played a crucial role in advancing the development of innovative aptasensors tailored for the precise detection of specific proteins. Aptamers offer several advantages over commonly used molecular recognition methods, such as antibodies. Recently, a variety of metal-based aptasensors have been established. These metallic nanomaterials encompass noble metal nanoparticles, metal oxides, metal-carbon nanotubes, carbon quantum dots, graphene-conjugated metallic nanostructures, as well as their nanocomposites, metal-organic frameworks (MOFs), and MXenes. In general, these materials provide enhanced sensitivity through signal amplification and transduction mechanisms. This review primarily focuses on the advancement of aptasensors based on metallic materials for the highly sensitive detection of protein targets, including enzymes and growth factors. Additionally, it sheds light on the challenges encountered in this field and outlines future prospects. We firmly believe that this review will offer a comprehensive overview and fresh insights into metallic nanomaterials-based aptasensors and their capabilities, paving the way for the development of innovative point-of-care (POC) diagnostic devices.

Identifiers

PMID38298588
PMCPMC10825927

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.