Evidence map›Paper›PMID 38298510›Full record

ArticleFrontiers in medicine2023

Change of glucometabolic activity per PSMA expression predicts survival in mCRPC patients non-responding to PSMA radioligand therapy: introducing a novel dual imaging biomarker.

Caroline Burgard, Jakob Engler, Arne Blickle, Mark Bartholomä, Stephan Maus, Andrea Schaefer-Schuler, Fadi Khreish, Samer Ezziddin, Florian Rosar

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04833517 (REALITY Study), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04833517 unknown statusnot on this map

REALITY Study: Analysis of a Prospective REgistry to Assess Outcome and Toxicity of Targeted RadionucLide TherapY in Patients With mCRPC in Clinical Routine.

Typeobservational_patient_registrySponsorUniversität des SaarlandesRan2016 to 2025Enrolled500ConditionsProstate Cancer Metastatic, Castration Resistant Prostatic Cancer, Advanced Prostate Carcinoma
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Real-world outcomes of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  3. Radionuclides Landscape in Prostate Cancer Theranostics.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Caroline Burgard *Department of Nuclear Medicine, Saarland University-Medical Center, Homburg, Germany.
Jakob EnglerDepartment of Nuclear Medicine, Saarland University-Medical Center, Homburg, Germany.
Arne BlickleDepartment of Nuclear Medicine, Saarland University-Medical Center, Homburg, Germany.
Mark BartholomäDepartment of Nuclear Medicine, Saarland University-Medical Center, Homburg, Germany.
Stephan MausDepartment of Nuclear Medicine, Saarland University-Medical Center, Homburg, Germany.
Andrea Schaefer-SchulerDepartment of Nuclear Medicine, Saarland University-Medical Center, Homburg, Germany.
Fadi KhreishDepartment of Nuclear Medicine, Saarland University-Medical Center, Homburg, Germany.
Samer EzziddinDepartment of Nuclear Medicine, Saarland University-Medical Center, Homburg, Germany.
Florian RosarDepartment of Nuclear Medicine, Saarland University-Medical Center, Homburg, Germany.
Saarland University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The value of [ Methods: Twenty-three mCRPC patients of a prospective registry (NCT04833517), who were treated with [ Results: Kaplan-Meier analyses showed no significant association with OS for each tested cGA (cGA Conclusion: The novel biomarker cGAP

Indexed as

dual imagingPET/CTprostate cancerPSMA—prostate-specific membrane antigenradioligand therapy

Identifiers

PMID38298510
PMCPMC10827880
OpenAlexW4390953404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.