ArticleFrontiers in medicine2023
The impact of paternal age on cumulative assisted reproductive technology outcomes.
Article in Frontiers in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Association between quality of life and pregnancy outcomes among infertility patients undergoing assisted reproduction technologies: a prospective cohort study.Annals of medicine · 2026Article
- Impact of male partner's age on IVF/ICSI pregnancy outcomes stratified by female age: a retrospective study of 1,703 treatment cycles.BMC pregnancy and childbirth · 2026Article
- Clinical Implications of Paternal Age in Assisted Reproduction: Integrating Sperm Epigenetic Evidence.Journal of clinical medicine · 2026Review
- An Artificial Intelligence-Based Model to Predict Pregnancy After Intrauterine Insemination: A Retrospective Analysis of 9501 Cycles.Journal of personalized medicine · 2025Article
- Patient-specific predictors of successful frozen embryo transfer using the freeze-all protocol: a retrospective observational study.Journal of Yeungnam medical science · 2025Article
- The impact of advanced paternal age on the live birth rate in patients undergoing Assisted Reproduction treatment: Findings from an analysis at a public reproductive center in Brazil.JBRA assisted reproduction · 2024Article
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Authors and funding
7 authors.
Funding
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Abstract
Objective: To investigate the impact of paternal age on cumulative live birth rate in ART. Design: Retrospective single-center cohort study. Patients: All female patients aged 18-43 years and male patients aged 18-60 years, who performed their first ART cycle between January 2018 and December 2020, were included. Main outcome measures: The primary outcome, cumulative live birth rate (cLBR), was estimated following fresh or frozen embryo transfers issued from an ART cycle. Secondary outcomes included the cumulative pregnancy rate (cPR) and miscarriage rate. Subgroup analyzes were performed as follows: men <45 and ≥ 45; female <35, 35-38, and > 38 years. Results: A total of 2,358 couples were included in this study. The sperm quantity of male patients within both age groups was divided in two groups: normal and abnormal, which were found to be in significantly equal proportions. There were significantly fewer current smokers in the male group ≥45. The cPR was 0.5301 in the group <45 and 0.3111 in the group ≥45, with a Conclusion: According to the results from our study, male age ≥ 45 has a significant impact on cumulative ART outcomes.
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