Evidence map›Paper›PMID 38298443›Full record

ArticleFrontiers in oncology2023

On-demand plerixafor added to high-dose cyclophosphamide and pegylated recombinant human granulocyte colony-stimulating factor in the mobilization of patients with multiple myeloma: a treatment with high effectiveness, convenient, and affordable cost.

Li-Qiong Hou, Jun-Ru Liu, Jing-Li Gu, Mei-Lan Chen, Li-Fen Kuang, Bei-Hui Huang, Wai-Yi Zou, Juan Li

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Li-Qiong HouDepartment of Hematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jun-Ru LiuDepartment of Hematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Jing-Li GuDepartment of Hematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Mei-Lan ChenDepartment of Hematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Li-Fen KuangDepartment of Hematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Bei-Hui HuangDepartment of Hematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Wai-Yi ZouDepartment of Hematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Juan LiDepartment of Hematology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
The First Affiliated Hospital, Sun Yat-sen University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The combination of high-dose cyclophosphamide (HD-Cy) (3g/m Methods: A retrospective analysis was conducted on 350 MM patients, which were categorized based on their mobilization regimens: Cy+PEG G-CSF+/-PXF (n=66), Cy+PEG G-CSF (n=91), Cy+ G-CSF (n=169), and G-CSF+PXF (n=24). Results: Mobilization with Cy+PEG G-CSF+/-PXF(8.79)yielded a notably higher median CD34 Conclusion: The combination of on-demand PXF with HD-Cy and PEG G-CSF offers a cost-effective approach with a high mobilization success rate, manageable side effects, and the convenience of fewer injections. It stands as a promising mobilization strategy for MM patients.

Indexed as

cyclophosphamidemultiple myelomapegylated granulocyte colony-stimulating factorplerixaforstem cell mobilization

Identifiers

PMID38298443
PMCPMC10827932
OpenAlexW4391016434

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.