Evidence map›Paper›PMID 38298376›Full record

ArticleFrontiers in cellular neuroscience2023

Insulin-like growth factor 2 (IGF-2) rescues social deficits in NLG3

Rocco Pizzarelli, Domenico Pimpinella, Christian Jacobs, Alice Tartacca, Uarda Kullolli, Hannah Monyer, Cristina M Alberini, Marilena Griguoli

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Rocco Pizzarelli *European Brain Research Institute (EBRI), Rome, Italy.
Domenico Pimpinella *European Brain Research Institute (EBRI), Rome, Italy.
Christian JacobsEuropean Brain Research Institute (EBRI), Rome, Italy.
Alice TartaccaEuropean Brain Research Institute (EBRI), Rome, Italy.
Uarda KullolliEuropean Brain Research Institute (EBRI), Rome, Italy.
Hannah MonyerEuropean Brain Research Institute (EBRI), Rome, Italy.
Cristina M AlberiniCenter for Neural Science, New York University, New York, NY, United States.
Marilena GriguoliEuropean Brain Research Institute (EBRI), Rome, Italy.
European Brain Research Institute · ITGerman Cancer Research Center · DEInstitute of Molecular Biology and Pathology · ITNew York University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorders (ASDs) comprise developmental disabilities characterized by impairments of social interaction and repetitive behavior, often associated with cognitive deficits. There is no current treatment that can ameliorate most of the ASDs symptomatology; thus, identifying novel therapies is urgently needed. Here, we used the Neuroligin 3 knockout mouse (NLG3

Indexed as

ASDshippocampusIGF-2NLG3 -/y mousesocial behavior

Identifiers

PMID38298376
PMCPMC10827848
OpenAlexW4390953334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.