Evidence map›Paper›PMID 38298205›Full record

ArticleFrontiers in human neuroscience2023

Early childhood malnutrition impairs adult resting brain function using near-infrared spectroscopy.

Kassandra Roger, Phetsamone Vannasing, Julie Tremblay, Maria L Bringas Vega, Cyralene P Bryce, Arielle Rabinowitz, Pedro Antonio Valdes-Sosa, Janina R Galler, Anne Gallagher

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in human neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Facing stress and inflammation: From the cell to the planet.World journal of experimental medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Kassandra RogerLION Lab, Sainte-Justine University Hospital Research Center, University of Montreal, Montreal, QC, Canada.
Phetsamone VannasingLION Lab, Sainte-Justine University Hospital Research Center, University of Montreal, Montreal, QC, Canada.
Julie TremblayLION Lab, Sainte-Justine University Hospital Research Center, University of Montreal, Montreal, QC, Canada.
Maria L Bringas VegaMOE Key Lab for Neuroinformation, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China.
Cyralene P BryceBarbados Nutrition Study, Bridgetown, Barbados.
Arielle RabinowitzMontreal Neurological Institute, McGill University, Montreal, QC, Canada.
Pedro Antonio Valdes-SosaMOE Key Lab for Neuroinformation, The Clinical Hospital of Chengdu Brain Science Institute, University of Electronic Science and Technology of China, Chengdu, China.
Janina R GallerDivision of Pediatric Gastroenterology and Nutrition, MassGeneral Hospital for Children, Boston, MA, United States.
Anne GallagherLION Lab, Sainte-Justine University Hospital Research Center, University of Montreal, Montreal, QC, Canada.
Université de Montréal · CAUniversity of Electronic Science and Technology of China · CNBarbados Community College · BBMaineGeneral Medical Center · USMontreal Neurological Institute and Hospital · CA

Funding

Transgenerational Effects of Undernutrition on ChildrenR01HD060986 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI GALLER, JANINA R. · 2011 to 2015
$4.9M
NICHD NIH HHS R01 HD060986
6 · The paper itself

Abstract

Introduction: Early childhood malnutrition affects 200+ million children under 5 years of age worldwide and is associated with persistent cognitive, behavioral and psychiatric impairments in adulthood. However, very few studies have investigated the long-term effects of childhood protein-energy malnutrition (PEM) on brain function using a functional hemodynamic brain imaging technique. Objective and methods: This study aims to investigate functional brain network alterations using near infrared spectroscopy (NIRS) in adults, aged 45-51 years, from the Barbados Nutrition Study (BNS) who suffered from a single episode of malnutrition restricted to their first year of life (n = 26) and controls (n = 29). A total of 55 individuals from the BNS cohort underwent NIRS recording at rest. Results and discussion: Using functional connectivity and permutation analysis, we found patterns of increased Pearson's correlation with a specific vulnerability of the frontal cortex in the PEM group (ps < 0.05). Using a graph theoretical approach, mixed ANCOVAs showed increased segregation (ps = 0.0303 and 0.0441) and decreased integration (

Indexed as

functional connectivitygraph theoryNIRSprotein-energy malnutritionresting-state

Identifiers

PMID38298205
PMCPMC10827877
OpenAlexW4390953476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.