Evidence map›Paper›PMID 38298094›Full record

ArticleBiomolecules & therapeutics2024

Hydroxychavicol Inhibits In Vitro Osteoclastogenesis via the Suppression of NF-κB Signaling Pathway.

Sirada Srihirun, Satarat Mathithiphark, Chareerut Phruksaniyom, Pitchanun Kongphanich, Wisutthaporn Inthanop, Thanaporn Sriwantana, Salunya Tancharoen, Nathawut Sibmooh, Pornpun Vivithanaporn

Open access · hybridAbstract read
In one paragraph

Article in Biomolecules & therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Bactericidal Activities of Nanoemulsion ContainingAntibiotics (Basel, Switzerland) · 2025
    Article
  3. PTHrP participates in the bone destruction of middle ear cholesteatoma via promoting macrophage differentiation into osteoclasts induced by RANKL.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Sirada SrihirunDepartment of Pharmacology, Faculty of Dentistry, Mahidol University, Bangkok 10400, Thailand.
Satarat MathithipharkFaculty of Allied Health Sciences, Burapha University, Chonburi 20131, Thailand.
Chareerut PhruksaniyomDepartment of Pharmacology, Faculty of Dentistry, Mahidol University, Bangkok 10400, Thailand.
Pitchanun KongphanichFaculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Wisutthaporn InthanopFaculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand.
Thanaporn SriwantanaChakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan 10540, Thailand.
Salunya TancharoenDepartment of Pharmacology, Faculty of Dentistry, Mahidol University, Bangkok 10400, Thailand.
Nathawut SibmoohChakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan 10540, Thailand.
Pornpun VivithanapornChakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samut Prakan 10540, Thailand.
Mahidol University · THRamathibodi Hospital · THBurapha University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxychavicol, a primary active phenolic compound of betel leaves, previously inhibited bone loss

Indexed as

Bone resorptionHydroxychavicolNF-κBOsteoclastOsteoporosisRAW264.7

Identifiers

PMID38298094
PMCPMC10902706
OpenAlexW4391446789

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.