Evidence map›Paper›PMID 38297990›Full record

ArticleThe oncologist2024

Development of an Electronic Decision Aid Tool to Facilitate Mainstream Genetic Testing in Ovarian Cancer Patients.

Kristen M Shannon, Devanshi Patel, Jessica M Jonas, Erica L Blouch, Stephanie R Hicks, Mackenzie Wooters, Meredith Seidel, Carly F Grant, Margaret M Emmet, Daniel C Chung and 1 more

Abstract read
In one paragraph

Article in The oncologist, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kristen M ShannonMassachusetts General Hospital Center for Cancer Risk Assessment, Boston, MA, USA.ORCID 0000-0003-4141-3672
Devanshi PatelMassachusetts General Hospital Center for Cancer Risk Assessment, Boston, MA, USA.
Jessica M JonasMassachusetts General Hospital Center for Cancer Risk Assessment, Boston, MA, USA.
Erica L BlouchMassachusetts General Hospital Center for Cancer Risk Assessment, Boston, MA, USA.
Stephanie R HicksMassachusetts General Hospital Center for Cancer Risk Assessment, Boston, MA, USA.ORCID 0000-0002-0485-0008
Mackenzie WootersMassachusetts General Hospital Center for Cancer Risk Assessment, Boston, MA, USA.
Meredith SeidelMassachusetts General Hospital Center for Cancer Risk Assessment, Boston, MA, USA.
Carly F GrantMassachusetts General Hospital Center for Cancer Risk Assessment, Boston, MA, USA.
Margaret M EmmetMassachusetts General Hospital Center for Cancer Risk Assessment, Boston, MA, USA.
Daniel C ChungMassachusetts General Hospital Center for Cancer Risk Assessment, Boston, MA, USA.
Karen SepuchaHealth Decision Sciences Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

Funding

VectorP30CA006516 · NCI · DANA-FARBER CANCER INSTITUTE · PI A. Heather Eliassen · 1985 to 2026
$330.6M
NCI NIH HHS P30 CA006516
6 · The paper itself

Abstract

backgroundMultigene panel testing is an important component of cancer treatment plans and risk assessment, but there are many different panel options and choosing the most appropriate panel can be challenging for health care providers and patients. Electronic tools have been proposed to help patients make informed decisions about which gene panel to choose by considering their preferences and priorities. MATERIALS AND

methodsAn electronic decision aid (DA) tool was developed in line with the International Patient Decision Aids Standards collaboration. The multidisciplinary project team collaborated with an external health care communications agency and the MGH Cancer Center Patient and Family Advisory Council (PFAC) to develop the DA. Surveys of genetic counselors and patients were used to scope the content, and alpha testing was used to refine the design and content.

resultsSurveys of genetic counselors (n = 12) and patients (n = 228) identified common themes in discussing panel size and strategies for helping patients decide between panels and in identifying confusing terms for patients and distribution of patients' choices. The DA, organized into 2 major sections, provides educational text, graphics, and videos to guide patients through the decision-making process. Alpha testing feedback from the PFAC (n = 4), genetic counselors (n = 3) and a group of lay people (n = 8) identified areas to improve navigation, simplify wording, and improve layout.

conclusionThe DA developed in this study has the potential to facilitate informed decision-making by patients regarding cancer genetic testing. The distinctive feature of this DA is that it addresses the specific question of which multigene panel may be most suitable for the patient. Its acceptability and effectiveness will be evaluated in future studies.

Indexed as

Decision Support TechniquesGenetic CounselingGenetic TestingOvarian NeoplasmsAdultDecision MakingFemaleHumansMiddle Ageddecision aidgenetic counselinggenetic testingovarian cancershared decision-making

Identifiers

PMID38297990
PMCPMC11067819

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.