Evidence map›Paper›PMID 38297919›Full record

ArticleNMR in biomedicine2024

Contrast-free dynamic susceptibility contrast using sinusoidal and bolus oxygenation challenges.

Chau Vu, Jian Shen, Clio Gonzalez-Zacarias, Botian Xu, Koen Baas, Soyoung Choi, Aart Nederveen, John C Wood

Open access · greenAbstract read
In one paragraph

Article in NMR in biomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Chau VuDepartment of Biomedical Engineering, University of Southern California, Los Angeles, California, USA.
Jian ShenDepartment of Biomedical Engineering, University of Southern California, Los Angeles, California, USA.
Clio Gonzalez-ZacariasNeuroscience Graduate Program, University of Southern California, Los Angeles, California, USA.
Botian XuDepartment of Biomedical Engineering, University of Southern California, Los Angeles, California, USA.
Koen BaasDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands.
Soyoung ChoiNeuroscience Graduate Program, University of Southern California, Los Angeles, California, USA.
Aart NederveenDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands.
John C WoodDepartment of Biomedical Engineering, University of Southern California, Los Angeles, California, USA.
University of Southern California · USAmsterdam University Medical Centers · NLChildren's Hospital of Los Angeles · US

Funding

Southern California Clinical and Translational Science InstituteUL1TR001855 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Thomas A Buchanan, Michele D. Kipke · 2016 to 2026
$81.3M
Southern California Clinical and Translational Science InstituteUL1TR000130 · NCATS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BUCHANAN, THOMAS A · 2012 to 2015
$36.0M
Neuromodulatory Mechanisms and Regional Autonomic Dysregulation in the Development of Pain in Sickle Cell Disease PatientsU01HL117718 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI COATES, THOMAS DUANE, KHOO, MICHAEL C K · 2013 to 2017
$9.6M
Interactive software for semiautomated analysis of structural brain imagesR01NS074980 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEAHY, RICHARD M, SHATTUCK, DAVID W · 2011 to 2021
$5.0M
Brain Blood Flow, Oxygenation, and Cognition in Adult Onset Iron Deficiency AnemiaR01NS117430 · NINDS · CHILDREN'S HOSPITAL OF LOS ANGELES · PI JOHN C WOOD · 2023 to 2026
$2.7M
Cerebrovascular reserve and white matter disease in patients with anemiaR01HL136484 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI WOOD, JOHN C · 2018 to 2021
$2.5M
Neurological Consequences of AnemiaF31NS106828 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI CHOI, SOYOUNG · 2018 to 2020
$116k
NCATS NIH HHS UL1 TR000130NCATS NIH HHS UL1 TR001855NCRR NIH HHS 5UL1-TR000130-05NHLBI NIH HHS 1R01-HL136484-01A1NHLBI NIH HHS 1U01-HL-117718-01NHLBI NIH HHS R01 HL136484NHLBI NIH HHS U01 HL117718NIH HHS R01-NS074980NINDS NIH HHS 1F31NS106828-01A1NINDS NIH HHS F31 NS106828NINDS NIH HHS R01 NS074980NINDS NIH HHS R01 NS117430
6 · The paper itself

Abstract

Deoxygenation-based dynamic susceptibility contrast (dDSC) MRI uses respiratory challenges as a source of endogenous contrast as an alternative to gadolinium injection. These gas challenges induce T2*-weighted MRI signal losses, after which tracer kinetics modeling was applied to calculate cerebral perfusion. This work compares three gas challenges, desaturation (transient hypoxia), resaturation (transient normoxia), and SineO

Indexed as

Contrast MediaGadoliniumAdultBrainCerebrovascular CirculationFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedOxygenReproducibility of ResultsContrast MediaGadoliniumOxygencerebral perfusiondeoxyhemoglobindynamic susceptibility contrastgadolinium‐freehypoxiarespiratory challenge

Identifiers

PMID38297919
PMCPMC10987281
OpenAlexW4391446322

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.