Evidence map›Paper›PMID 38297892›Full record

ArticleBJPsych open2024

Psychotropic medicines' prevalence, patterns and effects on cognitive and physical function in older adults with intellectual disability in Ireland: longitudinal cohort study, 2009-2020.

Marina Odalović, Ashleigh Gorman, Aviejay Paul, Philip McCallion, Éilish Burke, Malcolm MacLachlan, Mary McCarron, Martin C Henman, Maeve Moran, Juliette O'Connell and 4 more

Open access · goldAbstract read
In one paragraph

Article in BJPsych open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 3 countries.

Marina OdalovićSchool of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Ireland; and Trinity Centre for Ageing and Intellectual Disability, Trinity College Dublin, Ireland.ORCID https://orcid.org/0000-0002-3050-8361
Ashleigh GormanSchool of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Ireland; and Trinity Centre for Ageing and Intellectual Disability, Trinity College Dublin, Ireland.ORCID https://orcid.org/0000-0001-8524-2399
Aviejay PaulSchool of Social Work, College of Public Health, Temple University, Philadelphia, USA.
Philip McCallionSchool of Social Work, College of Public Health, Temple University, Philadelphia, USA.
Éilish BurkeSchool of Nursing and Midwifery, Trinity College Dublin, Ireland; and Trinity Centre for Ageing and Intellectual Disability, Trinity College Dublin, Ireland.
Malcolm MacLachlanNational Clinical Programme for People with Disabilities, Health Service Executive, Dublin, Ireland; Assisting Living & Learning Institute, Maynooth University, Ireland; and Psychology Department, Maynooth University, Ireland.
Mary McCarronSchool of Nursing and Midwifery, Trinity College Dublin, Ireland; and Trinity Centre for Ageing and Intellectual Disability, Trinity College Dublin, Ireland.
Martin C HenmanSchool of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Ireland; and Trinity Centre for Ageing and Intellectual Disability, Trinity College Dublin, Ireland.
Maeve MoranFaculty of Learning Disability Psychiatry, College of Psychiatrists of Ireland, Dublin, Ireland.
Juliette O'ConnellSchool of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Ireland; and Trinity Centre for Ageing and Intellectual Disability, Trinity College Dublin, Ireland.
Michael WalshNational Clinical Programme for People with Disabilities, Health Service Executive, Dublin, Ireland.
Rohit ShankarPeninsula Medical School, University of Plymouth, UK.ORCID https://orcid.org/0000-0002-1183-6933
Caitriona RyanSchool of Nursing and Midwifery, Trinity College Dublin, Ireland; and Trinity Centre for Ageing and Intellectual Disability, Trinity College Dublin, Ireland.
Máire O'DwyerSchool of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, Ireland; and Trinity Centre for Ageing and Intellectual Disability, Trinity College Dublin, Ireland.
Trinity College Dublin · IETemple University · USHealth Service Executive · IENational University of Ireland, Maynooth · IEUniversity of Plymouth · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe frequent prescribing of psychotropics and high prevalence of polypharmacy among older adults with intellectual disabilities require close monitoring.

aimsTo describe change in prevalence, predictors and health outcomes of psychotropic use during the four waves (2009/2010, 2013/2014, 2016/2017, 2019/2020) of the Intellectual Disability Supplement to the Irish Longitudinal Study on Ageing (IDS-TILDA).

methodEligible participants were adults (≥40 years) with intellectual disabilities who participated in all four waves of IDS-TILDA and who reported medication use for the entire period. Differences between groups were tested using Cochran's

resultsAcross waves (433 participants) there were no significant differences in prevalence of psychotropic use (61.2-64.2%) and psychotropic polypharmacy (42.7-38.3%). Antipsychotics were the most used subgroup, without significant change in prevalence between waves (47.6-44.6%). A significant decrease was observed for anxiolytics (26.8-17.6%;

conclusionsThe study indicates an increase in usage of some classes of psychotropic, a reduction in others and no change in the relatively high rate of antipsychotic use over 10 years in a cohort of older adults with intellectual disabilities and consequent risk of psychotropic polypharmacy and medication-related harm.

Indexed as

antidepressantsantipsychoticsIntellectual disabilitypolypharmacypsychotropic medicines

Identifiers

PMID38297892
PMCPMC10897684
OpenAlexW4391443264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.