Evidence map›Paper›PMID 38297836›Full record

ReviewBiophysical journal2024

Machine learning in RNA structure prediction: Advances and challenges.

Sicheng Zhang, Jun Li, Shi-Jie Chen

Abstract readReview
In one paragraph

Review in Biophysical journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. APDB: A Large-Scale Repository of Predicted 2D and 3D Aptamer Structures.Journal of chemical information and modeling · 2026
    Article
  2. Accurate RNA-Ligand Binding Site Prediction Based on a Multi-Channel Graph Neural Network.Interdisciplinary sciences, computational life sciences · 2026
    Article
  3. Review
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  10. Transformers in RNA structure prediction: A review.Computational and structural biotechnology journal · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sicheng ZhangDepartment of Physics and Institute of Data Science and Informatics, University of Missouri, Columbia, Missouri.
Jun LiDepartment of Physics and Institute of Data Science and Informatics, University of Missouri, Columbia, Missouri.
Shi-Jie ChenDepartment of Physics and Institute of Data Science and Informatics, University of Missouri, Columbia, Missouri; Department of Biochemistry, University of Missouri, Columbia, Missouri. Electronic address: chenshi@missouri.edu.

Funding

New methods for computational modeling of RNA structuresR35GM134919 · NIGMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI SHI-JIE CHEN · 2020 to 2026
$3.3M
NIGMS NIH HHS R35 GM134919
6 · The paper itself

Abstract

RNA molecules play a crucial role in various biological processes, with their functionality closely tied to their structures. The remarkable advancements in machine learning techniques for protein structure prediction have shown promise in the field of RNA structure prediction. In this perspective, we discuss the advances and challenges encountered in constructing machine learning-based models for RNA structure prediction. We explore topics including model building strategies, specific challenges involved in predicting RNA secondary (2D) and tertiary (3D) structures, and approaches to these challenges. In addition, we highlight the advantages and challenges of constructing RNA language models. Given the rapid advances of machine learning techniques, we anticipate that machine learning-based models will serve as important tools for predicting RNA structures, thereby enriching our understanding of RNA structures and their corresponding functions.

Indexed as

Machine LearningNucleic Acid ConformationRNAModels, MolecularRNA

Identifiers

PMID38297836
PMCPMC11393687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.