Evidence map›Paper›PMID 38297460›Full record

ArticlePalliative medicine2024

Revised European Association for Palliative Care (EAPC) recommended framework on palliative sedation: An international Delphi study.

Séverine M Surges, Holger Brunsch, Birgit Jaspers, Kathi Apostolidis, Antonella Cardone, Carlos Centeno, Nathan Cherny, Àgnes Csikós, Robin Fainsinger, Eduardo Garralda and 9 more

Abstract read
In one paragraph

Article in Palliative medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. End-of-life care for people with severe and persistent mental illness and a life-limiting disease: An umbrella review.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Pooled it
  4. Article
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  6. End-of-life sedation and gendered narrative registers: a longitudinal qualitative study of spouses bereaved by cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
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  18. Continuous sedation in adolescent and young adult cancer patients under home-based end-of-life care.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Séverine M SurgesDepartment of Palliative Medicine, University Hospital Bonn, Bonn, Germany.ORCID 0000-0001-6991-1767
Holger BrunschDepartment of Palliative Medicine, University Hospital Bonn, Bonn, Germany.
Birgit JaspersDepartment of Palliative Medicine, University Hospital Bonn, Bonn, Germany.
Kathi ApostolidisEuropean Cancer Patient Coalition, Brussels, Belgium.
Antonella CardoneCancer Patients Europe, Brussels, Belgium.
Carlos CentenoATLANTES Global Observatory of Palliative Care, Institute for Culture and Society, University of Navarra, Pamplona, Spain.
Nathan ChernyDepartment of Medical Oncology, Shaare Zedek Medical Center, Jerusalem, Israel.
Àgnes CsikósDepartment of Primary Health Care, Department of Hospice-Palliative Care, University of Pecs Medical School, Pecs, Hungary.
Robin FainsingerUniversity of Alberta, Edmonton, AB, Canada.
Eduardo GarraldaATLANTES Global Observatory of Palliative Care, Institute for Culture and Society, University of Navarra, Pamplona, Spain.
Julie LingEuropean Association for Palliative Care, Vilvoorde, Belgium.ORCID 0000-0001-6187-8253
Johan MentenLaboratory of Experimental Radiotherapy, KU Leuven, Leuven, Belgium.
Sebastiano MercadanteMain Regional Centre for Pain Relief and Palliative/Supportive Care, La Maddalena Cancer Centre, Palermo, Italy.ORCID 0000-0001-9859-6487
Daniela MosoiuMedical Faculty, Transilvania University, Brasov, Romania.
Sheila PayneInternational Observatory on End-of-Life Care, Faculty of Health and Medicine, Lancaster University, Lancaster, UK.ORCID 0000-0001-6982-9181
Nancy PrestonInternational Observatory on End-of-Life Care, Faculty of Health and Medicine, Lancaster University, Lancaster, UK.ORCID 0000-0003-2659-2342
Lieve Van den BlockVUB-UGhent End-of-Life Care Research Group, Vrije Universiteit Brussel, Brussels, Belgium.
Jeroen HasselaarDepartment of Primary Care, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands.
Lukas RadbruchDepartment of Palliative Medicine, University Hospital Bonn, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe European Association for Palliative Care (EAPC) acknowledges palliative sedation as an important, broadly accepted intervention for patients with life-limiting disease experiencing refractory symptoms. The EAPC therefore developed 2009 a framework on palliative sedation. A revision was needed due to new evidence from literature, ongoing debate and criticism of methodology, terminology and applicability.

aimTo provide evidence- and consensus-based guidance on palliative sedation for healthcare professionals involved in end-of-life care, for medical associations and health policy decision-makers.

designRevision between June 2020 and September 2022 of the 2009 framework using a literature update and a Delphi procedure.

settingEuropean.

participantsInternational experts on palliative sedation (identified through literature search and nomination by national palliative care associations) and a European patient organisation.

resultsA framework with 42 statements for which high or very high level of consensus was reached. Terminology is defined more precisely with the terms

conclusionsThis is the first framework on palliative sedation using a strict consensus methodology. It should serve as comprehensive and soundly developed information for healthcare professionals.

Indexed as

AnesthesiaDeep SedationTerminal CareConsensusDelphi TechniqueHumansPalliative CareconsensusDeep sedationDelphi consensus (as the MeSH term consensus is not further defined)end-of-lifeEuropepalliative carePalliative sedation (as the MeSH Terms refers only to one type of sedation)practice guidelinesufferingterminal care

Identifiers

PMID38297460
PMCPMC10865771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.