Evidence map›Paper›PMID 38297357›Full record

ArticleClinical hypertension2024

Elevated blood pressure among children born to women with obstructed labour in Eastern Uganda: a cohort study.

David Mukunya, Milton W Musaba, Brendah Nambozo, Faith Oguttu, Brian Tonny Makoko, Agnes Napyo, Ritah Nantale, Solomon Wani, Josephine Tumuhamye, Prossy Auma and 8 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical hypertension, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

David MukunyaDepartment of Community and Public Health, Busitema University, P.O. Box 1460, Mbale, Uganda.
Milton W MusabaDepartment of Obstetrics and Gynecology, Busitema University, P.O. Box 1460, Mbale, Uganda.
Brendah NambozoDepartment of Community and Public Health, Busitema University, P.O. Box 1460, Mbale, Uganda. 262nbrendah@gmail.com.
Faith OguttuDepartment of Community and Public Health, Busitema University, P.O. Box 1460, Mbale, Uganda.
Brian Tonny MakokoDepartment of Community and Public Health, Busitema University, P.O. Box 1460, Mbale, Uganda.
Agnes NapyoDepartment of Community and Public Health, Busitema University, P.O. Box 1460, Mbale, Uganda.
Ritah NantaleDepartment of Community and Public Health, Busitema University, P.O. Box 1460, Mbale, Uganda.
Solomon WaniDepartment of Community and Public Health, Busitema University, P.O. Box 1460, Mbale, Uganda.
Josephine TumuhamyeMakerere University Hospital, Makerere University Kampala, Kampala, Uganda.
Prossy AumaDepartment of Obstetrics and Gynecology, Mbale Regional Referral Hospital, P.O. Box 921, Mbale, Uganda.
Ketty AtimDepartment of Obstetrics and Gynecology, Mbale Regional Referral Hospital, P.O. Box 921, Mbale, Uganda.
Joan WamulugwaDepartment of Pediatrics, Mbale Regional Referral Hospital, P.O. Box 921, Mbale, Uganda.
Doreck NahuriraDepartment of Obstetrics and Gynecology, Busitema University, P.O. Box 1460, Mbale, Uganda.
Dedan OkelloDepartment of Pediatrics and Child Health, Busitema University, P.O. Box 1460, Mbale, Uganda.
Lawrence SsegawaDepartment of Research, Sanyu Africa Research Institute, P.O. Box 2190, Mbale, Uganda.
Julius WandabwaDepartment of Obstetrics and Gynecology, Busitema University, P.O. Box 1460, Mbale, Uganda.
Sarah KiguliDepartment of Pediatrics and Child Health, Makerere University, P.O. Box 7062, Kampala, Uganda.
Martin ChebetDepartment of Pediatrics and Child Health, Busitema University, P.O. Box 1460, Mbale, Uganda.
Busitema University · UGMakerere University · UGMbale Hospital · UGSanyu Africa Research Institute · UG

Funding

Health Professions Education and training for strengthening the health system and services in UgandaR25TW011213 · FIC · MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES · PI KIGULI, SARAH · 2018 to 2022
$3.4M
FIC NIH HHS 1R25TW011213FIC NIH HHS R25 TW011213
6 · The paper itself

Abstract

backgroundGlobally, high systolic blood pressure accounts for 10.8 million deaths annually. The deaths are disproportionately higher among black people. The reasons for this disparity are poorly understood, but could include a high burden of perinatal insults such as birth asphyxia. Therefore, we aimed to assess the incidence of elevated blood pressure and to explore associated factors among children born to women with obstructed labour.

methodsWe followed up children born to women with obstructed labour aged 25 to 44 months at Mbale regional referral hospital that had participated in the sodium bicarbonate trial ( Trial registration number PACTR201805003364421) between October 2021 and April 2022. Our primary outcome was elevated blood pressure defined as blood pressure (either systolic or diastolic or both) ≥ the 90th percentile for age, height, and sex in the reference population based on the clinical practice guideline for screening and management of high blood pressure in children and adolescents. We used logistic regression to estimate odds ratios between selected exposures and elevated blood pressure.

resultsThe incidence of elevated blood pressure was (39/140, 27.9%: 95% (CI: 20.6-36.1)). Participants aged three years and above had twice the odds of elevated blood pressure as those aged less than three years (Adjusted odds ratio (AOR) 2.46: 95% CI (1.01-5.97). Female participants had 2.81 times the odds of elevated blood pressure as their male counterparts (AOR 2.81 95% CI (1.16-6.82). Participants with reduced estimated glomerular filtration rate had 2.85 times the odds of having elevated blood pressure as those with normal estimated glomerular filtration rate (AOR 2.85 95% CI (1.00-8.13). We found no association between arterial cord lactate, stunting, wealth index, exclusive breastfeeding, food diversity and elevated blood pressure.

conclusionOur findings show a high incidence of elevated blood pressure among children. We encourage routine checking for elevated blood pressure in the pediatric population particularly those with known risk factors.

Indexed as

Birth asphyxiaElevated blood pressureObstructed labourPediatric hypertensionUganda

Identifiers

PMID38297357
PMCPMC10832100
OpenAlexW4392787613

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.