Evidence map›Paper›PMID 38297249›Full record

ArticleBMC psychiatry2024

Gender differences in prevalence and associations between cognitive symptoms and suicidal ideation in patients with recurrent major depressive disorder: findings from the Chinese NSSD study.

Ruizhi Mao, Chenglei Wang, Lvchun Cui, David Mellor, Zhiguo Wu, Yiru Fang

Open access · goldAbstract read
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Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Ruizhi MaoClinical Research Center and Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chenglei WangShanghai Changning District Mental Health Center, Shanghai, China.
Lvchun CuiClinical Research Center and Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
David MellorSchool of Psychology, Deakin University, Melbourne, Australia.
Zhiguo WuDepartment of Psychological Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, 160 Pujian Road, Shanghai, 200127, China. zhiguo_wu@yeah.net.
Yiru FangClinical Research Center and Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yirufang@aliyun.com.
Shanghai Jiao Tong University · CNDeakin University · AURenji Hospital · CNShanghai Changning Mental Health Center · CNShanghai Mental Health Center · CN

Funding

Key Supporting Projects of Clinical Research Center of Shanghai Mental Health Center SHDC2020CR6023National Natural Science Foundation of China 81771465Shanghai Key Project of Science and Technology 2018SHZDZX05Shanghai University of Medicine & Health Sciences Foundation 20MC2020005Shanghai Yangpu District Health Commission Foundation 22YPZB10the Capability Promotion Project for Research-oriented Doctor at SMHC 2021-YJXYS-03
6 · The paper itself

Abstract

backgroundThis study aimed to explore gender differences in associations between cognitive symptoms and suicidal ideation (SI) among patients with recurrent major depressive disorder (MDD).

methodsWe recruited 1222 patients with recurrent MDD from the National Survey on Symptomatology of Depression (NSSD), a survey designed to investigate the symptoms experienced during current major depressive episodes in China. A four-point Likert questionnaire was used to assess the frequency of cognitive symptoms and SI in the past two weeks.

resultsGender differences in clinical features and cognitive symptoms of participants with recurrent MDD were found. Specifically, male patients had a higher prevalence of memory loss, decreased verbal output, indecisiveness, and impaired interpersonal relationships, while female patients exhibited a higher prevalence of impaired social and occupational functioning (all P < 0.05). No significant difference in SI prevalence was found between male and female patients. The logistic regression analysis revealed that in male patients, SI was associated with indecisiveness and impaired interpersonal relationships. In female patients, reduced verbal output and impaired social and professional functions were also associated with SI in addition to the above-mentioned variables.

conclusionThe findings of gender differences in associations between cognitive symptoms and SI highlight the need to carefully assess gender-specific cognitive predictors of SI in patients with recurrent MDD. This has further implications for more targeted prevention and treatment strategies for SI based on gender.

Indexed as

Major Depressive DisorderSuicidal IdeationCognitionFemaleHumansMalePrevalenceSex FactorsCognitive symptomsGender differencesMajor depressive disorderRecurrent depressionSuicidal ideation

Identifiers

PMID38297249
PMCPMC10829390
OpenAlexW4391387738

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.