Evidence map›Paper›PMID 38297240›Full record

ArticleJournal of nanobiotechnology2024

Calcium phosphate coating enhances osteointegration of melt electrowritten scaffold by regulating macrophage polarization.

Yubo Shi, Weidong Tao, Wenjing Yang, Lei Wang, Zhennan Qiu, Xiaoli Qu, Jingyi Dang, Jiankang He, Hongbin Fan

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yubo Shi *Department of Orthopedic Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Weidong Tao *Department of Orthopedic Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Wenjing Yang *Xijing 986 Hospital Department, The Fourth Military Medical University, Xi'an, China.
Lei WangDepartment of Orthopedic Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Zhennan QiuState Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an, China.
Xiaoli QuState Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an, China.
Jingyi DangDepartment of Orthopedic Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China.
Jiankang HeState Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an, China.
Hongbin FanDepartment of Orthopedic Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China. fanhb@fmmu.edu.cn.
Air Force Medical University · CNXi'an Jiaotong University · CNXijing Hospital · CN

Funding

International Science and Technology Cooperation Keg Program project of Shaanxi Province 2023-GHZD-25National Natural Science Foundation of China 31971272
6 · The paper itself

Abstract

The osteoimmune microenvironment induced by implants plays a significant role in bone regeneration. It is essential to efficiently and timely switch the macrophage phenotype from M1 to M2 for optimal bone healing. This study examined the impact of a calcium phosphate (CaP) coating on the physiochemical properties of highly ordered polycaprolactone (PCL) scaffolds fabricated using melt electrowritten (MEW). Additionally, it investigated the influence of these scaffolds on macrophage polarization and their immunomodulation on osteogenesis. The results revealed that the CaP coated PCL scaffold exhibited a rougher surface topography and higher hydrophilicity in comparison to the PCL scaffold without coating. Besides, the surface morphology of the coating and the release of Ca

Indexed as

OsteogenesisTissue ScaffoldsBone RegenerationCalcium PhosphatesMacrophagesPhosphatidylinositol 3-KinasesCalcium PhosphatesPhosphatidylinositol 3-KinasesCalcium phosphateMacrophage polarizationMelt electrowrittenOsteointegrationPolycaprolactone

Identifiers

PMID38297240
PMCPMC10829397
OpenAlexW4391387683

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.