Evidence map›Paper›PMID 38297083›Full record

ArticleOncogene2024

Blocking LBH expression causes replication stress and sensitizes triple-negative breast cancer cells to ATR inhibitor treatment.

Koteswararao Garikapati, In-Chi Young, Sunhwa Hong, Priyamvada Rai, Chaitanya Jain, Karoline J Briegel

Abstract read
PubMed Publisher
In one paragraph

Article in Oncogene, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Koteswararao GarikapatiDeWitt Daugherty Department of Surgery, Molecular Oncology Program, University of Miami Miller School of Medicine, Miami, FL, USA.
In-Chi YoungDeWitt Daugherty Department of Surgery, Molecular Oncology Program, University of Miami Miller School of Medicine, Miami, FL, USA.
Sunhwa HongDeWitt Daugherty Department of Surgery, Molecular Oncology Program, University of Miami Miller School of Medicine, Miami, FL, USA.
Priyamvada RaiDepartment of Radiation Oncology and Tumor Biology Program at the Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.ORCID 0000-0001-7822-7553
Chaitanya JainDepartment of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL, USA.
Karoline J BriegelDeWitt Daugherty Department of Surgery, Molecular Oncology Program, University of Miami Miller School of Medicine, Miami, FL, USA. kbriegel@med.miami.edu.ORCID 0000-0003-2661-509X
University of Miami · US

Funding

Tumor Biology Research ProgramP30CA240139 · NCI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI George S. Grills · 2019 to 2026
$24.1M
Cell-Intrinsic Regulation of the Mammary Stem Cell NicheR01GM113256 · NIGMS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI BRIEGEL, KAROLINE JOSEFINE · 2015 to 2019
$1.5M
NCI NIH HHS P30 CA240139U.S. Department of Defense (United States Department of Defense) W81XWH-19-1-0255U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01GM113256
6 · The paper itself

Abstract

Triple-negative (ER

Indexed as

Triple Negative Breast NeoplasmsAtaxia Telangiectasia Mutated ProteinsCell CycleCell Cycle ProteinsCell Line, TumorHumansNeoplasm Recurrence, LocalProtein Kinase InhibitorsTranscription FactorsAtaxia Telangiectasia Mutated ProteinsATR protein, humanCell Cycle ProteinsLBH protein, humanProtein Kinase InhibitorsTranscription Factors

Identifiers

PMID38297083
OpenAlexW4391385508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.