ArticlePituitary2024
Pituitary hypophysitis in granulomatosis with polyangiitis (GPA): a case series.
Article in Pituitary, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 4 citations in OpenAlex.
- Review
- Microscopic Polyangiitis With Pituitary Dysfunction and Spontaneous Renal Aneurysm Rupture.Journal of medical cases · 2026Article
- Pituitary stalk thickening: can a multiparametric MRI approach improve etiologic prediction?Pituitary · 2026Article
- Granulomatosis With Polyangiitis Manifesting With Diabetes Insipidus and Cranial Nerve Involvement: A Case Report and Review of the Literature.Clinical case reports · 2025Article
- Panhypophysitis and infundibulitis associated with granulomatosis with polyangiitis.Endocrinology, diabetes & metabolism case reports · 2025Article
- A Rare Case of Microscopic Polyangitis With Associated Transient Hypophysitis.JCEM case reports · 2025Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Granulomatosis with polyangiitis (GPA) rarely involves the pituitary gland. Pituitary involvement has been reported in ~ 1% of all cases of GPA. Most commonly, pituitary swelling and inflammation results in symptoms due to pituitary mass effect and arginine vasopressin deficiency. To date, there are no pituitary-specific treatment guidelines for this rare condition. We present three patients with GPA-related hypophysitis highlighting the spectrum of pituitary involvement. All three patients were successfully treated with immunosuppressive regimens that included rituximab (RTX). Following remission induction with high-dose glucocorticoids, patients received 6 monthly RTX for remission maintenance. RTX was well tolerated without significant side effects.
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Registered trials
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