Evidence map›Paper›PMID 38296843›Full record

ArticleThe Korean journal of internal medicine2024

Model for end-stage liver disease-3.0 vs. model for end-stage liver disease-sodium: mortality prediction in Korea.

Jeong Han Kim, Yong Joon Cho, Won Hyeok Choe, So Young Kwon, Byung-Chul Yoo

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Article in The Korean journal of internal medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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0cells of the map it votes in
6citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jeong Han KimDepartment of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
Yong Joon ChoDepartment of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
Won Hyeok ChoeDepartment of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
So Young KwonDepartment of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.
Byung-Chul YooDepartment of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThe model for end-stage liver disease (MELD) serves as an indicator for short-term mortality among patients diagnosed with liver cirrhosis (LC) and is used to prioritize patients for liver transplantation. In 2021, the updated version of MELD, MELD-3.0, was introduced to improve the accuracy of the mortality prediction of MELD. Therefore, this study aimed to compare the efficacy of MELD 3.0 and MELD-Na in predicting mortality among Korean patients with LC.

methodsA retrospective review was conducted using the medical records of patients diagnosed with LC who were admitted to Konkuk University Hospital From 2011 to 2021. The study calculated the predictive values of MELD-Na and MELD-3.0 for 3- and 6-months mortality using the area under the receiver operating curve (AUROC) and compared the results using the DeLong test.

resultsOf the 3,034 patients enrolled in the study, 339 (11.2%) died within 3 months and 421 (14.4%) died within 6 months. The AUROCs values for predicting 3 months mortality were 0.846 for MELD-Na and 0.851 for MELD-3.0. The corresponding AUROC values for predicting 6 months mortality were 0.843 for MELD-Na and 0.848 for MELD-3.0. MELD-3.0 exhibited better discrimination ability than MELD-Na for both 3 (p = 0.03) and 6 months mortality (p = 0.01).

conclusionOur study found a significant difference between the performance of MELD-3.0 and MELD-Na in Korean patients with LC.

Indexed as

End Stage Liver DiseaseHumansLiver CirrhosisPredictive Value of TestsPrognosisRepublic of KoreaRetrospective StudiesROC CurveSeverity of Illness IndexSodiumSodiumCreatinineEnd stage liver diseaseLiver cirrhosisMortalitySodium

Identifiers

PMID38296843
PMCPMC10918373

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.